KIR2DL5/CD158f Products

KIR2DL5/CD158f Overexpression ...
KIR2DL5/CD158f Overexpression Lysate
Species: Hu
Applications: WB
Recombinant Human KIR2DL5/CD1 ...
Recombinant Human KIR2DL5/CD158f F...
Species: Hu
Applications: Bioactivity
Formulation Catalog # Availability Price  


Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells andsubsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies amonghaplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4,KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and bywhether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduceinhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins withthe short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase bindingprotein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules;thus, KIR proteins are thought to play an important role in regulation of the immune response. (provided by RefSeq)


Entrez Human
Uniprot Human
Product By Gene ID 57292
Alternate Names
  • CD158F
  • CD158F1
  • killer cell immunoglobulin-like receptor 2DL5A
  • killer cell immunoglobulin-like receptor KIR2DL5A
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A
  • killer-cell Ig-like receptor
  • KIR2DL5
  • KIR2DL5.1
  • KIR2DL5.3
  • KIR2DL5B

Pathways for KIR2DL5/CD158f

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Immune Response
Cell Activation
Innate Immune Response

PTMs for KIR2DL5/CD158f

Learn more about PTMs related to KIR2DL5/CD158f.


Bioinformatics Tool for KIR2DL5/CD158f

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