KIR2DL5/CD158f Products

Antibodies
KIR2DL5/CD158f Antibody
KIR2DL5/CD158f Antibody
H00057292-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
KIR2DL5/CD158f Antibody
KIR2DL5/CD158f Antibody
H00057292-D01P
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
KIR2DL5/CD158f Antibody (UP-R ...
KIR2DL5/CD158f Antibody (UP-R1) [PE]
NBP2-00190
Species: Hu
Applications: Flow, ICC/IF
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Lysates
KIR2DL5/CD158f Overexpression ...
KIR2DL5/CD158f Overexpression Lysa...
NBP2-06630
Applications: WB
Proteins
KIR2DL5/CD158f Recombinant Pr ...
KIR2DL5/CD158f Recombinant Protein
H00057292-G01
Species: Hu
RNAi
KIR2DL5/CD158f RNAi
KIR2DL5/CD158f RNAi
H00057292-R02
Species: Hu

Description

Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells andsubsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies amonghaplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4,KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and bywhether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduceinhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins withthe short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase bindingprotein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules;thus, KIR proteins are thought to play an important role in regulation of the immune response. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 57292
Alternate Names
  • killer-cell Ig-like receptor
  • CD158F
  • killer cell immunoglobulin-like receptor KIR2DL5A
  • KIR2DL5
  • KIR2DL5.1
  • KIR2DL5.3
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5
  • killer cell immunoglobulin-like receptor 2DL5A
  • KIR2DL5B
  • CD158F1
  • killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 5A

Pathways for KIR2DL5/CD158f

View related products by pathway and learn more about each of the pathways below.

Immune Response
Cell Activation
Innate Immune Response
Pathogenesis

PTMs for KIR2DL5/CD158f

Learn more about PTMs related to KIR2DL5/CD158f.

Phosphorylation

Bioinformatics Tool for KIR2DL5/CD158f

Discover related pathways, diseases and genes to KIR2DL5/CD158f. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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