Kir2.2 Products

Antibodies
Kir2.2 Antibody (S124B-38)
Kir2.2 Antibody (S124B-38)
NBP2-12901
Species: Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Kir2.2 Antibody
Kir2.2 Antibody
NBP1-89696
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Kir2.2 Antibody
Kir2.2 Antibody
NBP1-46736
Species: Hu
Applications: WB, IHC, IHC-Fr, IHC-P
Host: Rabbit Polyclonal
Lysates
Kir2.2 Overexpression Lysate ...
Kir2.2 Overexpression Lysate (Native)
NBP2-06575
Applications: WB
Proteins
Kir2.2 Recombinant Protein
Kir2.2 Recombinant Protein
H00003768-P01
Species: Hu
Applications: WB, ELISA, PA
Kir2.2 Recombinant Protein An ...
Kir2.2 Recombinant Protein Antigen
NBP1-89696PEP
Species: Hu
Applications: AC
RNAi
Kir2.2 RNAi
Kir2.2 RNAi
H00003768-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

FUNCTION: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium. Tissue specificity: Highest level in cerebellum. Moderately found in kidney, forebrain and skeletal muscle. Not detected in uterus, liver and pancreas. Subcellular location: Membrane, Multi-pass membrane protein.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 3768
Alternate Names
  • Inward rectifier K(+) channel Kir2.2v
  • kcnj12x
  • Inward rectifier K(+) channel Kir2.2
  • inward rectifier K(+) channel Kir2.6
  • potassium inwardly-rectifying channel, subfamily J, inhibitor 1
  • hkir2.2x
  • hIRK1
  • hIRK
  • Kir2.2v
  • ATP-sensitive inward rectifier potassium channel 12
  • Kir2.2
  • KCNJN1FLJ14167
  • IRK2IRK-2
  • Potassium channel, inwardly rectifying subfamily J member 12
  • potassium inwardly-rectifying channel, subfamily J, member 12

Pathways for Kir2.2

View related products by pathway and learn more about each of the pathways below.

Pathogenesis
Localization
Transport
Regeneration
Translation
Aging
Metaphase

PTMs for Kir2.2

Learn more about PTMs related to Kir2.2.

Phosphorylation

Bioinformatics Tool for Kir2.2

Discover related pathways, diseases and genes to Kir2.2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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