KCNN3 Products

Antibodies
KCNN3 Antibody
KCNN3 Antibody
NBP2-14144
Species: Hu, Mouse, Rat
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
KCNN3 Overexpression Lysate ( ...
KCNN3 Overexpression Lysate (Native)
NBP2-05209
Applications: WB
KCNN3 Overexpression Lysate ( ...
KCNN3 Overexpression Lysate (Native)
NBL1-12195
Applications: WB
Proteins
KCNN3 Recombinant Protein
KCNN3 Recombinant Protein
H00003782-P01
Species: Hu
Applications: WB, ELISA, PA
KCNN3 Partial Recombinant Pro ...
KCNN3 Partial Recombinant Protein
H00003782-Q01
Species: Hu
Applications: WB, ELISA, PA
KCNN3 Recombinant Protein
KCNN3 Recombinant Protein
H00003782-P02
Species: Hu
Applications: WB, ELISA, PA
RNAi
KCNN3 RNAi
KCNN3 RNAi
H00003782-R01
Species: Hu
KCNN3 RNAi
KCNN3 RNAi
H00003782-R02
Species: Hu

Description

Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. This gene is a member of the KCNN family of potassium channel genes. Two transcript variants encoding two different isoforms have been found for this gene. One of the variants lacks the CAG repeat regions.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 3782
Alternate Names
  • SKCa3
  • hSK3
  • SK3K3
  • KCa2.3SKCA3small conductance calcium-activated potassium channel protein 3
  • SKCa 3
  • potassium intermediate/small conductance calcium-activated channel, subfamilyN, member 3

PTMs for KCNN3

Learn more about PTMs related to KCNN3.

Biotinylation

Bioinformatics Tool for KCNN3

Discover related pathways, diseases and genes to KCNN3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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