Species: Hu
Applications: WB, ELISA, Func, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Mu
Applications: WB, IHC, ELISA(Cap)
Host: Goat Polyclonal
Species: Hu
Applications: WB, IHC, ICC/IF
Host: Goat Polyclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Species: Hu
Applications: AC
Description
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Mouse
Human
|
| Product By Gene ID |
50848 |
| Alternate Names |
- CD321 antigen
- F11 receptor
- JAM-1
- JAM1CD321
- JAMA
- JAM-A
- JCAMJAM
- Junctional adhesion molecule 1Platelet F11 receptor
- junctional adhesion molecule A
- PAM-1KAT
- Platelet adhesion molecule 1
|
![Immunocytochemistry JAM-A Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/JAM-A_AF1103_Immunocytochemistry_7256.jpg)
![Sandwich ELISA JAM-A Antibody Pair [HRP]](http://images.novusbio.com/fullsize/JAM-A-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79667-img0001.jpg)
