JAB1 Products

Antibodies
JAB1 Antibody (2B12)
JAB1 Antibody (2B12)
Species: Hu, Mk
Applications: WB, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
JAB1 Antibody
JAB1 Antibody
NBP1-84370
Species: Hu, Mu, Rt, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
JAB1 Overexpression Lysate (N ...
JAB1 Overexpression Lysate (Native)
NBL1-09383
Applications: WB
Proteins
JAB1 Recombinant Protein
JAB1 Recombinant Protein
H00010987-P01
Species: Hu
Applications: WB, ELISA, PA
JAB1 Recombinant Protein Anti ...
JAB1 Recombinant Protein Antigen
NBP1-84370PEP
Species: Hu
Applications: AC
RNAi
JAB1 RNAi
JAB1 RNAi
H00010987-R01
Species: Hu

Description

The protein encoded by the JAB1 gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. (provided by RefSeq)

Bioinformatics

Entrez Human
Mouse
Rat
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 10987
Alternate Names
  • EC 3.4
  • Jun activation domain-binding protein 1
  • COP9 signalosome complex subunit 5
  • MOV-34
  • SGN5MGC3149
  • JAB138 kDa Mov34 homolog
  • CSN5COP9 (constitutive photomorphogenic, Arabidopsis, homolog) subunit 5
  • Signalosome subunit 5
  • COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)

Research Areas for JAB1

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Bioinformatics Tool for JAB1

Discover related pathways, diseases and genes to JAB1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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