ITM2C Products

Antibodies
ITM2C Antibody
ITM2C Antibody
AF4904
Species: Hu
Applications: WB
Host: Sheep Polyclonal
ITM2C Antibody
ITM2C Antibody
NBP2-17001
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ITM2C Antibody
ITM2C Antibody
H00081618-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
ITM2C Overexpression Lysate ( ...
ITM2C Overexpression Lysate (Denat...
H00081618-T01
Species: Hu
Applications: WB
ITM2C Overexpression Lysate ( ...
ITM2C Overexpression Lysate (Native)
NBL1-12084
Applications: WB
ITM2C Overexpression Lysate ( ...
ITM2C Overexpression Lysate (Native)
NBL1-12085
Applications: WB
RNAi
ITM2C RNAi
ITM2C RNAi
H00081618-R02
Species: Hu
ITM2C RNAi
ITM2C RNAi
H00081618-R01
Species: Hu
ITM2C RNAi
ITM2C RNAi
H00081618-R03
Species: Hu

Description

ITM2C also known as Integral membrane protein 2C, has 3 isoforms, an isoform 1that is 267 amino acid and 30 kDa, an isoform 2 that is 220 amino acid and 25 kDa, and an isoform 3 that is 230 amino acid and 26 kDa; most commonly found in the brain tissue; acts as negative regulator of beta amyloid peptide production, may inhibit the processing of APP by blocking its access to alpha- and beta-secretase, appears to be a poor gamma-secretase cleavage inhibitor, and may play a role in TNF-induced cell death and neuronal differentiation. Studies are being performed on the relationship of this protein to anemia of prematurity, cerebritis, anemia, dementia, influenza, gastric cancer, and neuronitis. The protein has been shown to interact with BACE1, APP, STMN2, STT3A, RNF7, and FURIN proteins in negative regulation of neuron projection development, induction of programmed cell death, and neuron differentiation pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 81618
Alternate Names
  • Transmembrane protein BRI3
  • integral membrane protein 3
  • Cerebral protein 14
  • BRICHOS domain containing 2C
  • hRPC.1050_D_4
  • ITM3
  • E25
  • BRI3E25C
  • BRICD2C
  • integral membrane protein 2C

Bioinformatics Tool for ITM2C

Discover related pathways, diseases and genes to ITM2C. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.