ISYNA1 Products

Description

ISYNA1 is a gene that codes for a protein which is a key enzyme in the myo-inositol biosynthesis pathway which works to convert a glucose 6-phosphate into a 1-myo-inositol 1-phosphate, as well as a rate-limiting enzyme in the synthesis of all compounds containing inositol, and is highly expressed in the testis, ovary, heart, placenta, and pancreas. ISYNA1 has three isoforms with lengths of 558, 430, and 504 amino acids and weights of approximately 61, 47, and 55 kDa respectively. Current studies are being done on several diseases and disorders relating to this gene including synostosis, Whipple disease, cerebral palsy, osteonecrosis, bipolar disorder, candidiasis, cerebtitis, osteoarthritis, and malaria. ISYNA1 has also been shown to have interactions with NME2, PPP2CA, RPS15A, CAP2, and EEF2 in pathways such as inositol phosphate metabolism pathways.

Bioinformatics

Entrez	51477 Human
Uniprot	NM_016368 Human NP_057452 Human Q9NPH2 Human
Product By Gene ID	51477
Alternate Names	EC 5.5.1.4 hINO1 hIPS Ino1 INO1 INOS inositol-3-phosphate synthase 1 IPSIPS 1 MI-1-P synthase MIP synthase Myo-inositol 1-phosphate synthase A1 Myo-inositol-1-phosphate synthase

Research Areas for ISYNA1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis