IRAK3 Products

Antibodies
IRAK3 Antibody
IRAK3 Antibody
NBP1-76782
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
IRAK3 Antibody
IRAK3 Antibody
AF6264
Species: Hu
Applications: WB
Host: Sheep Polyclonal
IRAK3 Antibody (1C9)
IRAK3 Antibody (1C9)
H00011213-M07
Species: Hu, Mu, Rt
Applications: WB, ELISA
Host: Mouse Monoclonal
Antibody Pairs
IRAK3 Antibody Pair
IRAK3 Antibody Pair
H00011213-PW1
Species: Hu
Applications: WB, IP
Lysates
IRAK3 Overexpression Lysate ( ...
IRAK3 Overexpression Lysate (Denat...
H00011213-T01
Species: Hu
Applications: WB
IRAK3 Overexpression Lysate ( ...
IRAK3 Overexpression Lysate (Native)
NBL1-12027
Applications: WB
Proteins
Recombinant Human IRAK3 Prote ...
Recombinant Human IRAK3 Protein
H00011213-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human IRAK3 Prote ...
Recombinant Human IRAK3 Protein
H00011213-Q01
Species: Hu
Applications: WB, ELISA, PA
IRAK3 Recombinant Protein Ant ...
IRAK3 Recombinant Protein Antigen
NBP1-83094PEP
Species: Hu
Applications: AC
RNAi
IRAK3 RNAi
IRAK3 RNAi
H00011213-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
IRAK3 RNAi
IRAK3 RNAi
H00011213-R03
Species: Hu
Applications: RNAi, RNAi SP

Description

IRAK3 is a novel member in the IRAK/Pelle family. IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and play a central role in IL-1R/TLR mediated inflammatory responses. Interleukin-1 (IL-1) and lipopolysaccharide (LPS)induces cellular response through IL-1 receptor (IL-1R) and Toll like receptors (TLR). IL-1 receptor associated kinase (IRAK and IRAK2) mediates the activation of NF-kB by IL-1/Toll receptors (Wesche H et al.1999,Muzio M et al.1997), which is a pivotal transcription factor mediating inflammatory and immune response. A novel member in theIRAK/Pelle family was recently identified and designated IRAK-M (Cao Z et al.1996). IRAKs associate with IL-1/Toll receptors after IL-1 or LPS stimulation and thedominant negative mutants of IRAKs inhibit IL-1 orLPS induced NF-kB activation. Members inIRAK/Pelle family play a central role in IL-1R/TLRmediated inflammatory responses to cytokine IL-1and LPS.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Mouse
Product By Gene ID 11213
Alternate Names
  • IRAK-3
  • ASRT5
  • EC 2.7.11.1
  • IL-1 receptor-associated kinase M
  • FLJ13601
  • IRAK-M
  • IRAKM
  • interleukin-1 receptor-associated kinase 3

Research Areas for IRAK3

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Immunology
Innate Immunity
Protein Kinase

PTMs for IRAK3

Learn more about PTMs related to IRAK3.

Phosphorylation
Acetylation
Cleavage
Methylation

Bioinformatics Tool for IRAK3

Discover related pathways, diseases and genes to IRAK3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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