INTS6 Products

Antibodies
INTS6 Antibody
INTS6 Antibody
NB100-86990
Species: Hu, Bovine, Equine, Porcine, Rabbit, Rhesus Macaque
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
INTS6 Antibody
INTS6 Antibody
NBP1-85302
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
INTS6 Antibody
INTS6 Antibody
NBP1-88029
Species: Hu, Mouse, Rat
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
INTS6 Overexpression Lysate ( ...
INTS6 Overexpression Lysate (Native)
NBP2-08537
Applications: WB
INTS6 Overexpression Lysate ( ...
INTS6 Overexpression Lysate (Native)
NBP2-07487
Applications: WB
Proteins
INTS6 Partial Recombinant Pro ...
INTS6 Partial Recombinant Protein
H00026512-Q01
Species: Hu
Applications: WB, ELISA, PA
INTS6 Recombinant Protein Ant ...
INTS6 Recombinant Protein Antigen
NBP1-85302PEP
Species: Hu
Applications: AC
INTS6 Recombinant Protein Ant ...
INTS6 Recombinant Protein Antigen
NBP1-88029PEP
Species: Hu
Applications: AC
RNAi
INTS6 RNAi
INTS6 RNAi
H00026512-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The tumor suppressor gene DICE1 is located within a previously reported critical region of loss of heterozygosity on chromosome 13q14.3. Expression of the remaining DICE1 allele is down-regulated in non-small cell lung carcinomas. In IGF-IR transformed Balb/c 3T3, DICE1 substantially suppressed growth in soft agar. These results demonstrate that DICE1 has a growth-suppressing activity and interferes with anchorage-independent growth of IGF-IR transformed tumor cells dependent upon IGF-I signaling.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 26512
Alternate Names
  • Protein deleted in cancer 1
  • Protein DDX26
  • DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26
  • Int6
  • Notchl2
  • DBI1
  • INT6
  • RNA helicase HDB
  • HDB
  • DICE1DBI-1DDX26ADDX26DEAD box protein
  • DKFZp434B105
  • integrator complex subunit 6

Pathways for INTS6

View related products by pathway and learn more about each of the pathways below.

Cell Growth
Ribosome Biogenesis
Induction Of Apoptosis
Cell Cycle
G1 Phase
Dna Repair
Mrna Processing
Localization
Rna Splicing

Research Areas for INTS6

Find related products by research area and learn more about each of the different research areas below.

Cancer
Growth and Development
Neuronal Cell Markers
Tumor Suppressors

PTMs for INTS6

Learn more about PTMs related to INTS6.

Methylation
Cleavage

Bioinformatics Tool for INTS6

Discover related pathways, diseases and genes to INTS6. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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