Species: Hu
Applications: Flow, CyTOF-ready
Host: Human Monoclonal
Species: Hu, Po
Applications: Flow, ICC/IF, Binding Activity, ChIP
Host: Mouse Monoclonal
Species: Hu
Applications: Flow, CyTOF-ready
Host: Human Monoclonal
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Bioactivity
Species: Mu
Applications: Bioactivity
Description
The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria. (1-4) The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer. (1,2)
Bioinformatics
| Product By Gene ID |
3676 |
| Alternate Names |
- 269C wild type
- CD49 antigen-like family member D
- CD49d antigen
- CD49d
- CD49Dantigen CD49D, alpha-4 subunit of VLA-4 receptor
- IA4
- integrin alpha 4
- integrin alpha-4 subunit
- integrin alpha-4
- Integrin alpha-IV
- integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
- MGC90518
- very late activation protein 4 receptor, alpha 4 subunit
- VLA-4 subunit alpha
|
![Flow Cytometry Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Unconjugated]](http://images.novusbio.com/fullsize2/Integrin_alpha_4_beta_7_MAB10078_Flow_Cytometry_22998.jpg)
![N/A Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu117) [Unconjugated]](http://images.novusbio.com/fullsize/mab10078_human-integrin-alpha-4-beta-7-vedolizumab-mab-cl-hu117-25420248315766.jpg)
![Flow Cytometry Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu143) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab10548_human-integrin-alpha-4-beta-7-abrilumab-mab-clone-hu143-flow-cytometry-296202016191.jpg)
![N/A Integrin alpha 4 beta 7/LPAM-1 Antibody (Hu143) [Unconjugated]](http://images.novusbio.com/fullsize/mab10548_human-integrin-alpha-4-beta-7-abrilumab-mab-clone-hu143-25420248315757.jpg)
![Binding Activity Integrin alpha 4 beta 7/LPAM-1 [Unconjugated]](http://images.novusbio.com/fullsize/11509-a3_recombinant-human-integrin-4-7-lpam-1-fc-protein-cf-binding-activity-1142024122754.jpg)
![SDS-PAGE Integrin alpha 4 beta 7/LPAM-1 [Unconjugated]](http://images.novusbio.com/fullsize/11509-a3_recombinant-human-integrin-4-7-lpam-1-fc-protein-cf-sds-page-1142024124639.jpg)