IKK epsilon/IKBKE Products

Antibodies
IKK epsilon/IKBKE Antibody (3 ...
IKK epsilon/IKBKE Antibody (3C5)
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
IKK epsilon/IKBKE Antibody (3 ...
IKK epsilon/IKBKE Antibody (346909...
MAB3199
Species: Hu, Mu, Rt
Applications: WB, ICC
Host: Mouse Monoclonal
IKK epsilon/IKBKE Antibody [U ...
IKK epsilon/IKBKE Antibody [Unconj...
AF3199
Species: Hu
Applications: WB, ICC
Host: Goat Polyclonal
Lysates
IKK epsilon/IKBKE Overexpress ...
IKK epsilon/IKBKE Overexpression L...
NBP2-07392
Applications: WB
Proteins
IKK epsilon/IKBKE Recombinant ...
IKK epsilon/IKBKE Recombinant Prot...
NBP1-83114PEP
Species: Hu
Applications: AC
IKK epsilon/IKBKE Recombinant ...
IKK epsilon/IKBKE Recombinant Protein
P4704
Species: Hu
Applications: Func, PAGE
IKK epsilon/IKBKE Peptide
IKK epsilon/IKBKE Peptide
NBP1-76800PEP
Species: Hu
Applications: AC
RNAi
IKK epsilon/IKBKE RNAi
IKK epsilon/IKBKE RNAi
H00009641-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Nuclear Factor kappa B (NF-kB) is a ubiquitous transcription factor and an essential mediator of gene expression during the activation of immune and inflammatory responses. NF-kB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-kB is associated with IkB proteins in the cytoplasm of the cell, which inhibit NF-kB activity. IkB proteins are phosphorylated by an IkB kinase complex consisting of at least three proteins, IKKa, IKKb, and IKKg. Isolated from a cDNA library of LPS-stimulated mouse macrophage cells, a novel molecule in the IKK complex has been recently identified and designated IKKi and/or IKKe. IKKe is required for the activation of NF-kB by mitogens and T cell receptors but not by TNFa or IL-1. LPS increases the IKKe mRNA level in mouse macrophage cell lines. This protein has significant sequence homology with kinase domains of IKKa and IKKb. Overexpression of wild type IKKe in cells phosphorylates Ser32 and Ser36 of IkBa.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 9641
Alternate Names
  • EC 2.7.11
  • I-kappa-B kinase epsilon
  • IkBKE
  • IKKI
  • EC 2.7.11.10
  • IKK-epsilon
  • inhibitor of nuclear factor kappa-B kinase subunit epsilon
  • IKK-E
  • inducible IkappaB kinase
  • Inducible I kappa-B kinase
  • KIAA0151IKK-related kinase epsilon
  • IKKEMGC125297
  • IKK-iMGC125295
  • MGC125294
  • inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon

Research Areas for IKK epsilon/IKBKE

Find related products by research area and learn more about each of the different research areas below.

Cancer
Phospho-Specific
Protein Kinase

Bioinformatics Tool for IKK epsilon/IKBKE

Discover related pathways, diseases and genes to IKK epsilon/IKBKE. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.