IKB zeta Products

Description

IkappaBzeta (also known as MAIL and INAP) is an ankyrin-repeat-containing nuclear protein that is highly homologous to the IkappaB family member Bcl-3. Transcription of IkappaBzeta is upregulated by stimulation with TLR ligands, IL-1 and IL-6 in cultured B-lymphocytes and monocytes/macrophages, but only faintly so in T-lymphocytes, fibroblasts, and endothelial cells. IkappaB-zeta preferentially associates with the NF-kappaB subunit p50 rather than p65 and recombinant IkappaB-zeta proteins inhibit the DNA binding of the p65/p50 heterodimer and the p50/p50 homodimer.

Bioinformatics

Entrez	304005 Rat 64332 Human 80859 Mouse
Uniprot	NP_113607.1 Human Q9BYH8 Human
Product By Gene ID	64332
Alternate Names	FLJ30225 FLJ34463 IkappaBzeta ikappaBzeta I-kappa-B-zeta IkappaB-zeta ikbzeta IkB-zeta IL-1 inducible nuclear ankyrin-repeat protein INAPIkappa B-zeta variant 3 MAILIKBZikB-zeta Molecule possessing ankyrin repeats induced by lipopolysaccharide NF-kappa-B inhibitor zeta nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor