IBRDC2 Products

Antibodies
IBRDC2 Antibody (9H10)
IBRDC2 Antibody (9H10)
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
IBRDC2 Antibody (4F1)
IBRDC2 Antibody (4F1)
H00255488-M02
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
IBRDC2 Antibody
IBRDC2 Antibody
NBP2-37941
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
IBRDC2 Antibody Pair
IBRDC2 Antibody Pair
H00255488-PW1
Species: Hu
Applications: WB, IP
Lysates
IBRDC2 Overexpression Lysate ...
IBRDC2 Overexpression Lysate (Dena...
H00255488-T01
Species: Hu
Applications: WB
IBRDC2 Overexpression Lysate ...
IBRDC2 Overexpression Lysate (Native)
NBL1-15428
Applications: WB
Proteins
IBRDC2 Partial Recombinant Pr ...
IBRDC2 Partial Recombinant Protein
H00255488-Q01
Species: Hu
Applications: WB, ELISA, PA
IBRDC2 Recombinant Protein
IBRDC2 Recombinant Protein
H00255488-P01
Species: Hu
Applications: WB, ELISA, PA
IBRDC2 Recombinant Protein An ...
IBRDC2 Recombinant Protein Antigen
NBP2-37941PEP
Species: Hu
Applications: AC
RNAi
IBRDC2 RNAi
IBRDC2 RNAi
H00255488-R01
Species: Hu

Description

E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes UBE2L3 and UBE2L6in the form of a thioester and then directly transfers the ubiquitin to targeted substrates such as LCMT2, therebypromoting their degradation. Induces apoptosis via a TP53/p53-dependent but caspase-independent mechanism

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 255488
Alternate Names
  • EC 6.3.2
  • KIAA0161
  • P53RFP
  • p53-inducible RING finger protein
  • EC 6.3.2.-
  • IBR domain-containing protein 2
  • p53RFP
  • IBRDC2
  • E3 ubiquitin-protein ligase RNF144B
  • IBR domain containing 2
  • PIR2
  • bA528A10.3
  • ring finger protein 144BMGC71786

Diseases related to IBRDC2

Discover more about diseases related to IBRDC2.

Infectious Bovine Rhinotracheitis
Malignant Neoplasms
Neoplasms
Growth Arrest
Malignant Neoplasm Of Lung

Pathways for IBRDC2

View related products by pathway and learn more about each of the pathways below.

Cell Death
Cell Cycle
Induction Of Apoptosis
Localization

PTMs for IBRDC2

Learn more about PTMs related to IBRDC2.

Phosphorylation
Ubiquitination

Bioinformatics Tool for IBRDC2

Discover related pathways, diseases and genes to IBRDC2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related IBRDC2 Blog Posts

Check out the latest blog posts on IBRDC2.
The Latest Research on IBR-type E3 Ubiquitin Ligases
E3 ubiquitin ligases are standards in most antibody catalogs. These proteins are essential to the process of ubiquitination, which is expressed in protein pathways throughout the body and is often linked to disease states. It is widely used as a bioma...    Read more.
Read more IBRDC2 related blogs.