Species: Hu, Mu, Rt, Fe
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Rt
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
HtrA3 belongs to the human high-temperature requirement factor A (HtrA) family. HtrA3 has two isoforms (long and short), which are produced by alternative splicing. Similar to HtrA1, HtrA3 binds to various TGF-beta proteins and inhibits the signaling of BMP-4, -2 and TGF-beta 1. HtrA3 does not inhibit signaling originated from a constitutively active BMP receptor, indicating that the inhibition occurs upstream of the cell surface receptor.
Bioinformatics
| Entrez |
Rat
Mouse
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
94031 |
| Alternate Names |
- EC 3.4.21
- EC 3.4.21.-
- EC 3.4.21.108
- High-temperature requirement factor A3
- HtrA serine peptidase 3
- Pregnancy-related serine protease
- probable serine protease HTRA3
- Prsp
- PRSP
- serine protease HTRA3
- Tasp
|
