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HSPA8/HSC71/Hsc70 Products

Antibodies
HSPA8/HSC71/Hsc70 Antibody (1 ...
HSPA8/HSC71/Hsc70 Antibody (13D3)
NB120-2788
Western Blot HSPA8/HSC71/Hsc70 Antibody (13D3)
Immunocytochemistry/ Immunofluorescence HSPA8/HSC71/Hsc70 Antibody (13D3)
Immunohistochemistry-Paraffin HSPA8/HSC71/Hsc70 Antibody (13D3)
Immunocytochemistry/ Immunofluorescence HSPA8/HSC71/Hsc70 Antibody (13D3)
Immunocytochemistry/ Immunofluorescence HSPA8/HSC71/Hsc70 Antibody (13D3)
Immunocytochemistry/ Immunofluorescence HSPA8/HSC71/Hsc70 Antibody (13D3)
Immunohistochemistry-Paraffin HSPA8/HSC71/Hsc70 Antibody (13D3)
Immunohistochemistry-Paraffin HSPA8/HSC71/Hsc70 Antibody (13D3)
Immunoprecipitation HSPA8/HSC71/Hsc70 Antibody (13D3)
Western Blot HSPA8/HSC71/Hsc70 Antibody (13D3)
Western Blot HSPA8/HSC71/Hsc70 Antibody (13D3)
Western Blot HSPA8/HSC71/Hsc70 Antibody (13D3)
Western Blot HSPA8/HSC71/Hsc70 Antibody (13D3)
Western Blot HSPA8/HSC71/Hsc70 Antibody (13D3)
Knockdown Validated HSPA8/HSC71/Hsc70 Antibody (13D3)
Species: Hu, Mu, Rt, Bv, Fe, Fi, Ha, Pm
Applications: WB, Simple Western, Flow, ICC/IF, IHC, IP, B/N
Host: Mouse Monoclonal
HSPA8/HSC71/Hsc70 Antibody (1 ...
HSPA8/HSC71/Hsc70 Antibody (1B5) -...
NBP1-97868
Western Blot HSPA8/HSC71/Hsc70 Antibody (1B5) - BSA Free
Immunohistochemistry-Paraffin HSPA8/HSC71/Hsc70 Antibody (1B5) - BSA Free
Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Gp, Ha, Pm, Rb, Sh
Applications: WB, Simple Western, ELISA, Flow, ICC/IF, IHC, IP, MS
Host: Rat Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 NBP1-97868AF350
Alexa Fluor 532 NBP1-97868AF532
Alexa Fluor 594 NBP1-97868AF594
Alexa Fluor 750 NBP1-97868AF750
Biotin NBP1-97876-0.05mg
Biotin NBP1-97876-0.2mg
Biotin NBP1-97868B
CoraFluor 1 NBP1-97868CL1
DyLight 550 NBP1-97868R
DyLight 594 NBP1-97868DL594
DyLight 650 NBP1-97868C
FITC NBP1-97868F
HRP NBP1-97868H
Janelia Fluor 525 NBP1-97868JF525
Janelia Fluor 549 NBP1-97868JF549
Janelia Fluor 646 NBP1-97868JF646
Janelia Fluor 669 NBP1-97868JF669
mFluor Violet 450 SE NBP1-97868MFV450
mFluor Violet 500 SE NBP1-97868MFV500
mFluor Violet 610 SE NBP1-97868MFV610
Formulation Catalog # Availability Price  
BSA Free NBP1-97868-0.05mg
BSA Free NBP1-97868-0.2mg
BSA Free NBP1-97868-0.025mg
HSPA8/HSC71/Hsc70 Antibody (5 ...
HSPA8/HSC71/Hsc70 Antibody (521503...
MAB4148
Western Blot HSPA8/HSC71/Hsc70 Antibody (521503) [Unconjugated]
Immunocytochemistry HSPA8/HSC71/Hsc70 Antibody (521503) [Unconjugated]
Immunohistochemistry HSPA8/HSC71/Hsc70 Antibody (521503) [Unconjugated]
Simple Western HSPA8/HSC71/Hsc70 Antibody (521503) [Unconjugated]
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, ICC/IF
Host: Mouse Monoclonal
Conjugate Catalog # Availability Size Price
Alexa Fluor 350 FAB4148U-100UG
Alexa Fluor 405 FAB4148V-100UG
Alexa Fluor 488 FAB4148G-100UG
Alexa Fluor 532 FAB4148X-100UG
Alexa Fluor 594 FAB4148T-100UG
Alexa Fluor 647 FAB4148R-100UG
Alexa Fluor 700 FAB4148N-100UG
Alexa Fluor 750 FAB4148S-100UG
Alexa Fluor Plus 405 FAB4148AFP405-100UG
Alexa Fluor Plus 488 FAB4148AFP488-100UG
Alexa Fluor Plus 555 FAB4148AFP555-100UG
Alexa Fluor Plus 594 FAB4148AFP594-100UG
Alexa Fluor Plus 647 FAB4148AFP647-100UG
Alexa Fluor Plus 680 FAB4148AFP680-100UG
Allophycocyanin FAB4148A
Biotin FAB4148B
CoraFluor 1 FAB4148CL1
DyLight 350 FAB4148D
DyLight 405 FAB4148E
DyLight 488 FAB4148K
DyLight 550 FAB4148L
DyLight 594 FAB4148M
DyLight 650 FAB4148W
DyLight 680 FAB4148Y
DyLight 755 FAB4148Z
FITC FAB4148F
HRP FAB4148H
Janelia Fluor 525 FAB4148JF525
Janelia Fluor 549 FAB4148I
Janelia Fluor 646 FAB4148J
Janelia Fluor 669 FAB4148JF669
PE FAB4148P
PerCP FAB4148C
mFluor Violet 450 SE FAB4148MFV450
mFluor Violet 500 SE FAB4148MFV500
mFluor Violet 610 SE FAB4148MFV610
Formulation Catalog # Availability Price  
Carrier Free MAB4148-SP
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We have 21 HSPA8/HSC71/Hsc70 Antibodies
ELISA Kits
Human HSPA8/HSC71/Hsc70 - Re ...
Human HSPA8/HSC71/Hsc70 - Ready-T...
NBP3-31872
ELISA Human HSPA8/HSC71/Hsc70 - Ready-To-Use ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
Human HSPA8/HSC71/Hsc70 ELISA ...
Human HSPA8/HSC71/Hsc70 ELISA Kit ...
NBP3-31871
ELISA Human HSPA8/HSC71/Hsc70 ELISA Kit (Colorimetric)
Species: Hu
Applications: ELISA
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We have 2 HSPA8/HSC71/Hsc70 ELISA Kits
Lysates
HSPA8/HSC71/Hsc70 Overexpress ...
HSPA8/HSC71/Hsc70 Overexpression L...
NBL1-11755
Western Blot HSPA8/HSC71/Hsc70 Overexpression Lysate
Species: Hu
Applications: WB
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We have 1 HSPA8/HSC71/Hsc70 Lysate
Proteins
Recombinant Human HSPA8/HSC71 ...
Recombinant Human HSPA8/HSC71/Hsc7...
NBP1-30278
SDS-Page Recombinant Human HSPA8/HSC71/Hsc70 His Protein
Species: Hu
Applications: Func, PAGE
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We have 1 HSPA8/HSC71/Hsc70 Protein

Description

Hsp73 is a normal cell constituent which is synthesized in increased abundance under adverse environmental circumstances, such as non-physiological temperatures or treatment with amino acid analogues (1). Data has shown a molecular mechanism for cytokine-mediated posttranscriptional regulation of Bim mRNA by Hsc70, which binds to AU-rich elements (AREs) in the 3'-untranslated region of specific mRNAs and enhances their stability. The RNA binding potential of Hsc70 is regulated by cochaperones including Bag-4 (also SODD), CHIP, Hip, and Hsp40 (2). Hsp73 protein expression was detected in the cytoplasm of melanoma cells in primary tumors and metastases. In primary melanomas, the proportion of Hsp73 protein expressing cells correlated with tumor thickness which was found to be statistically significant (3).

Bioinformatics

Entrez
15481
Mouse
24468
Rat
3312
Human
Uniprot
AAH16179
Human
AAH16660
Human
NM_006597
Human
NP_005337
Human
NP_006588.1
Human
P11142
Human
Product By Gene ID 3312
Alternate Names
  • Heat shock 70 kDa protein 8
  • heat shock 70kD protein 8
  • heat shock 70kDa protein 8
  • heat shock cognate 71 kDa protein
  • heat shock cognate protein 54
  • heat shock cognate protein, 71-kDa
  • HSC54
  • HSC70heat shock 70kd protein 10
  • HSC71
  • HSP71
  • HSP73constitutive heat shock protein 70
  • HSPA10
  • LAP1
  • lipopolysaccharide-associated protein 1
  • LPS-associated protein 1
  • MGC131511
  • MGC29929
  • NIP71
  • N-myristoyltransferase inhibitor protein 71

Research Areas for HSPA8/HSC71/Hsc70

Find related products by research area and learn more about each of the different research areas below.

Membrane Trafficking and Chaperones

Related HSPA8/HSC71/Hsc70 Blog Posts

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Chaperone Mediated Autophagy (CMA) does it all!
By Christina Towers, PhD. The degradation of cellular proteins is a critical step of both regulation and quality control and results in the turn over and recycling of critical amino acids. The two main mechanisms o...    Read more.
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