Hsp90A/B Products


HSP90 is an abundantly and ubiquitously expressed heat shock protein. It is understood to exist in two principal forms alpha and beta, which share 85% sequence amino acid homology. The two isoforms of Hsp90 are expressed in the cytosolic compartment (1). Despite the similarities, HSP90alpha exists predominantly as a homodimer while HSP90beta exists mainly as a monomer.(2) From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex. (3-6) Furthermore, Hsp90 is highly conserved between species; having 60% and 78% amino acid similarity between mammalian and the corresponding yeast and Drosophila proteins, respectively. Hsp90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. Despite its label of being a heat-shock protein, hsp90 is one of the most highly expressed proteins in unstressed cells (1


Entrez Rat
Uniprot Human
Product By Gene ID 3320
Alternate Names
  • heat shock protein HSP 90-alpha
  • Heat shock 86 kDa
  • heat shock 90kD protein, alpha-like 4
  • heat shock 90kDa protein 1, alpha
  • heat shock 90kD protein 1, alpha-like 4
  • heat shock 90kD protein 1, alpha
  • HSPN
  • Hsp90
  • Hsp89
  • LAP2
  • HSP90N
  • FLJ31884
  • HSPC1HSP 86
  • HSP90AHSP86
  • Renal carcinoma antigen NY-REN-38
  • heat shock protein 90kDa alpha (cytosolic), class A member 1

PTMs for Hsp90A/B

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Bioinformatics Tool for Hsp90A/B

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