hnRNP-Q Products

Description

Heterogenous nuclear ribonucleoprotein (hnRNP) implicated in mRNA processing mechanisms. Component of the CRD-mediated complex that promotes MYC mRNA stability. Isoform 1, isoform 2 and isoform 3 are associated in vitro with pre-mRNA, splicing intermediates and mature mRNA protein complexes. Isoform 1 binds to apoB mRNA AU-rich sequences. Isoform 1 is part of the APOB mRNA editosome complex and may modulate the postranscriptional C to U RNA-editing of the APOB mRNA through either by binding to A1CF (APOBEC1 complementation factor), to APOBEC1 or to RNA itself. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Interacts in vitro preferentially with poly(A) and poly(U) RNA sequences. Isoform 3 may be involved in cytoplasmic vesicle-based mRNA transport through interaction with synaptotagmins

Bioinformatics

Entrez	10492 Human 56403 Mouse
Uniprot	AAH32643 Human AAH40844 Human AAH40844.1 Human O60506 Human
Product By Gene ID	10492
Alternate Names	Synaptotagmin-binding, cytoplasmic RNA-interacting protein HNRPQ Glycine- and tyrosine-rich RNA-binding protein heterogeneous nuclear ribonucleoprotein Q hnRNP-Q PP68 dJ3J17.2 GRYRBP HNRPQ1 NSAP1FLJ31626 GRY-RBPNS1-associated protein 1 hnRNP Q synaptotagmin binding, cytoplasmic RNA interacting protein

Diseases related to hnRNP-Q

Discover more about diseases related to hnRNP-Q.

Malignant Neoplasms
Hepatitis
Neurodegenerative Disorders
Neoplasms
Hepatitis C
Physiological Stress
Murine Hepatitis
Malignant Neoplasm Of Breast
Colonic Neoplasms
Ataxia
Malignant Tumor Of Colon
Carcinogenesis
Motor Neuron Disease
Mammary Neoplasms
Neurofibrillary Tangles
Spinal Muscular Atrophy
Liver Carcinoma
Nerve Degeneration
Multiple Endocrine Neoplasia Type 2b

Pathways for hnRNP-Q

View related products by pathway and learn more about each of the pathways below.

Translation
Transport
Mrna Transport
Localization
Rna Transport
Mrna Stabilization
Rna Interference
Translational Initiation
Intracellular Transport
Cell Proliferation
Cell Development
Synaptic Transmission
Neurogenesis
Syncytium Formation
Methylation
Protein Methylation
Rna Surveillance
Axis Specification
Cell Motility
Cell Cycle

PTMs for hnRNP-Q

Learn more about PTMs related to hnRNP-Q.

Phosphorylation
Methylation

Bioinformatics Tool for hnRNP-Q

Discover related pathways, diseases and genes to hnRNP-Q. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.