HLA DOB Products

Antibodies
HLA DOB Antibody
HLA DOB Antibody
NBP1-87469
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
HLA DOB Antibody
HLA DOB Antibody
H00003112-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
HLA DOB Antibody
HLA DOB Antibody
H00003112-D01P
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Antibody Pairs
HLA DOB Antibody Pair
HLA DOB Antibody Pair
H00003112-PW1
Species: Hu
Applications: WB, IP
Lysates
HLA DOB Overexpression Lysate ...
HLA DOB Overexpression Lysate (Den...
H00003112-T01
Species: Hu
Applications: WB
HLA DOB Overexpression Lysate ...
HLA DOB Overexpression Lysate (Nat...
NBL1-11582
Applications: WB
Proteins
HLA DOB Recombinant Protein A ...
HLA DOB Recombinant Protein Antigen
NBP1-87469PEP
Species: Hu
Applications: AC
HLA DOB Recombinant Protein
HLA DOB Recombinant Protein
NBP2-51696
Species: Hu
Applications: PAGE
RNAi
HLA DOB RNAi
HLA DOB RNAi
H00003112-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

HLA-DOB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DOA) and a beta chain (DOB), both anchored in the membrane. It is located in intracellular vesicles. DO suppresses peptide loading of MHC class II molecules by inhibiting HLA-DM. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 3112
Alternate Names
  • HLA class II histocompatibility antigen, DO beta chain
  • FLJ57033
  • DOB
  • MHC class II antigen DOB
  • major histocompatibility complex, class II, DO beta

Pathways for HLA DOB

View related products by pathway and learn more about each of the pathways below.

Transport
Intracellular Transport

Research Areas for HLA DOB

Find related products by research area and learn more about each of the different research areas below.

Asthma
Immunology

Bioinformatics Tool for HLA DOB

Discover related pathways, diseases and genes to HLA DOB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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