HLA DMB Products

Antibodies
HLA DMB Antibody
HLA DMB Antibody
NBP1-85326
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
HLA DMB Antibody (5G11)
HLA DMB Antibody (5G11)
H00003109-M06
Species: Hu
Applications: WB, ELISA, ICC/IF, IP
Host: Mouse Monoclonal
HLA DMB Antibody
HLA DMB Antibody
NBP1-31138
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
HLA DMB Antibody Pair
HLA DMB Antibody Pair
H00003109-PW2
Species: Hu
Applications: WB, IP
HLA DMB Antibody Pair
HLA DMB Antibody Pair
H00003109-PW1
Species: Hu
Applications: WB, IP
HLA DMB Antibody Pair
HLA DMB Antibody Pair
H00003109-PW4
Species: Hu
Applications: WB, IP
Lysates
HLA DMB Overexpression Lysate ...
HLA DMB Overexpression Lysate (Nat...
NBL1-11595
Applications: WB
HLA DMB Overexpression Lysate ...
HLA DMB Overexpression Lysate (Den...
H00003109-T03
Species: Hu
Applications: WB
Proteins
Recombinant Human HLA DMB Pro ...
Recombinant Human HLA DMB Protein
H00003109-Q01
Species: Hu
Applications: WB, ELISA, PA
HLA DMB Recombinant Protein A ...
HLA DMB Recombinant Protein Antigen
NBP1-85326PEP
Species: Hu
Applications: AC
RNAi
HLA DMB RNAi
HLA DMB RNAi
H00003109-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 3109
Alternate Names
  • DMB
  • MHC class II antigen DMB
  • MHC class II HLA-DMB
  • Really interesting new gene 7 protein
  • MHC class II antigen HLA-DM beta chain
  • D6S221E
  • RING7HLA class II histocompatibility antigen, DM beta chain
  • class II histocompatibility antigen, M beta chain
  • major histocompatibility complex, class II, DM beta

Pathways for HLA DMB

View related products by pathway and learn more about each of the pathways below.

Transport
Methylation
Intracellular Transport
Antigen Processing And Presentation
Histone Acetylation
Chromatin Modification
Pathogenesis
Localization

Research Areas for HLA DMB

Find related products by research area and learn more about each of the different research areas below.

Asthma
Diabetes Research
Immunology

PTMs for HLA DMB

Learn more about PTMs related to HLA DMB.

Acetylation
Methylation

Bioinformatics Tool for HLA DMB

Discover related pathways, diseases and genes to HLA DMB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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