HGD Products

Description

Homogentisate 1,2-dioxygenase (HGD) gene mutations are the molecular cause of alkaptonuria, a rare hereditary disorder of the phenylalanine catabolism. The highest expression of HGD is in the prostate, small intestine, colon, and liver. The HGD gene contains 14 exons. Conflicting reports have placed the gene at 3q2, 3q13.3-q21, 3q21-q24, 3q21-q23, or 3q25-q26.

Bioinformatics

Entrez	3081 Human
Uniprot	NP_000178 Human AAH71757.1 Human Q93099 Human AAH20792 Human
Product By Gene ID	3081
Alternate Names	AKU Homogentisicase EC 1.13.11.5 homogentisicase Homogentisic acid oxidase homogentisate oxidase Homogentisate oxygenase HGOFLJ94126 homogentisate 1,2-dioxygenase (homogentisate oxidase) homogentisate 1,2-dioxygenase

Diseases related to HGD

Discover more about diseases related to HGD.

Dysplasia
Barrett Esophagus
Adenocarcinoma
Esophageal Neoplasms
Malignant Neoplasms
Precancerous Conditions
Carcinoma
Neoplasms
Metaplasia
Esophageal Adenocarcinoma
Cell Transformation, Neoplastic
Adenoma
Colorectal Neoplasms
Ulcer
Gastroesophageal Reflux Disease
Colitis
Malignant Paraganglionic Neoplasm
Carcinogenesis
Alkaptonuria

Pathways for HGD

View related products by pathway and learn more about each of the pathways below.

Coagulation
Methylation
Cell Cycle
Cell Proliferation
Mitosis
Pathogenesis
Excretion
Secretion
Transport
Aging
Dna Methylation
Localization
Cell Death
Acid Secretion
Cell Adhesion
Programmed Cell Death
Gene Silencing
Proteolysis
Immune Response
Pigmentation

PTMs for HGD

Learn more about PTMs related to HGD.

Methylation
Demethylation
Biotinylation
Glycosylation
Cleavage

Bioinformatics Tool for HGD

Discover related pathways, diseases and genes to HGD. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.