Hexosaminidase A/HEXA Products

Antibodies
Hexosaminidase A/HEXA Antibod ...
Hexosaminidase A/HEXA Antibody (71...
MAB6237
Species: Hu
Applications: WB, IHC
Host: Mouse Monoclonal
Hexosaminidase A/HEXA Antibod ...
Hexosaminidase A/HEXA Antibody [Un...
AF6237
Species: Hu
Applications: WB, Simple Western
Host: Sheep Polyclonal
Hexosaminidase A/HEXA Antibod ...
Hexosaminidase A/HEXA Antibody
NBP1-74127
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
Hexosaminidase A/HEXA Antibod ...
Hexosaminidase A/HEXA Antibody Pair
H00003073-PW1
Species: Hu
Applications: WB, IP
Lysates
Hexosaminidase A/HEXA Overexp ...
Hexosaminidase A/HEXA Overexpressi...
H00003073-T01
Species: Hu
Applications: WB
Hexosaminidase A/HEXA Overexp ...
Hexosaminidase A/HEXA Overexpressi...
NBL1-11515
Applications: WB
Proteins
Hexosaminidase A/HEXA Recombi ...
Hexosaminidase A/HEXA Recombinant ...
NBP2-23121
Species: Hu
Applications: PAGE
Hexosaminidase A/HEXA Recombi ...
Hexosaminidase A/HEXA Recombinant ...
NBP2-30997PEP
Species: Hu
Applications: AC
Hexosaminidase A/HEXA Recombi ...
Hexosaminidase A/HEXA Recombinant ...
NBP2-52116
Species: Hu
Applications: PAGE
RNAi
Hexosaminidase A/HEXA RNAi
Hexosaminidase A/HEXA RNAi
H00003073-R01
Species: Hu

Description

HEXA encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I). [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 3073
Alternate Names
  • EC 3.2.1.52
  • EC 3.2.1
  • N-acetyl-beta-glucosaminidase subunit alpha
  • beta-hexosaminidase subunit alpha
  • Hexosaminidase subunit A
  • MGC99608
  • Beta-N-acetylhexosaminidase subunit alpha
  • TSD
  • hexosaminidase A (alpha polypeptide)

PTMs for Hexosaminidase A/HEXA

Learn more about PTMs related to Hexosaminidase A/HEXA.

Cleavage
Methylation
Phosphorylation
Nitration
Reduction
Glycosylation
Oxidation
Sulphation
Bromination
Acylation

Bioinformatics Tool for Hexosaminidase A/HEXA

Discover related pathways, diseases and genes to Hexosaminidase A/HEXA. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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