Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM]
Bioinformatics
Entrez |
Human Mouse |
Uniprot |
Human Human |
Product By Gene ID |
26091 |
Alternate Names |
- DKFZP564G092
- DKFZp564G092
- EC 6.3.2
- EC 6.3.2.-
- HECT domain and RCC1-like domain-containing protein 4
- hect domain and RLD 4
- KIAA1593probable E3 ubiquitin-protein ligase HERC4
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