HERC4 Products

Description

HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM]

Bioinformatics

Entrez	26091 Human 67345 Mouse
Uniprot	NP_071362 Human Q5GLZ8 Human
Product By Gene ID	26091
Alternate Names	DKFZp564G092 EC 6.3.2 DKFZP564G092 EC 6.3.2.- HECT domain and RCC1-like domain-containing protein 4 KIAA1593probable E3 ubiquitin-protein ligase HERC4 hect domain and RLD 4

Diseases related to HERC4

Discover more about diseases related to HERC4.

Spastic Ataxia, Charlevoix-saguenay Type
Nervousness
Ataxia
Fish Diseases
Trauma, Nervous System
Punctate Inner Choroidopathy
Rna Virus Infections

Pathways for HERC4

View related products by pathway and learn more about each of the pathways below.

Swimming
Gene Silencing
Cell Cycle
Aging
Dna Repair
Localization
Spermatogenesis

PTMs for HERC4

Learn more about PTMs related to HERC4.

Ubiquitination

Bioinformatics Tool for HERC4

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