GTPBP4 Products

Description

GTP-binding proteins are GTPases and function as molecular switches that can flip between two states: active, when GTP is bound, and inactive, when GDP is bound. 'Active' in this context usually means that the molecule acts as a signal to trigger other events in the cell. When an extracellular ligand binds to a G-protein-linked receptor, the receptor changes its conformation and switches on the trimeric G proteins that associate with it by causing them to eject their GDP and replace it with GTP. The switch is turned off when the G protein hydrolyzes its own bound GTP, converting it back to GDP. But before that occurs, the active protein has an opportunity to diffuse away from the receptor and deliver its message for a prolonged period to its downstream target. [provided by RefSeq]

Bioinformatics

Entrez	23560 Human
Uniprot	NM_012341 Human NP_036473.2 Human Q9BZE4 Human
Product By Gene ID	23560
Alternate Names	Chronic renal failure gene protein CRFGGTP-binding protein NGB FLJ10686 FLJ10690 G protein-binding protein CRFG GTP binding protein 4 NGB NOG1FLJ39774 nucleolar GTP-binding protein 1

Research Areas for GTPBP4

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction