Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, ICC/IF, IHC
Host: Mouse monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
GRF2 encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
Human
Human
Human
Human
|
| Product By Gene ID |
2889 |
| Alternate Names |
- C3GGRF2guanine nucleotide-releasing factor 2 (specific for crk proto-oncogene)
- CRK SH3-binding GNRP
- DKFZp781P1719
- Guanine nucleotide-releasing factor 2
- Protein C3G
- Rap guanine nucleotide exchange factor (GEF) 1
- rap guanine nucleotide exchange factor 1
|
Research Areas for GRF2
Find related products by research area and learn more about each of the different research areas below.
Signal Transduction
