GRB10 Products

Description

The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of the encoded protein inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]

Bioinformatics

Entrez	2887 Human
Uniprot	AAH24285 Human NP_001001550 Human NP_001001550.1 Human NP_001001555 Human Q13322 Human
Product By Gene ID	2887
Alternate Names	GRB10 adapter protein GRB10 adaptor protein Grb-10 GRBIR GRB-IR growth factor receptor-bound protein 10 Insulin receptor-binding protein Grb-IR IRBP KIAA0207 maternally expressed gene 1 MEG1 RSS

Research Areas for GRB10

Find related products by research area and learn more about each of the different research areas below.

Cancer