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GPR10 (Prolactin releasing hormone receptor/hGR3) is a Releasing Hormone Receptor that controls the secretion of prolactin from the anterior pituitary. Prolactin releasing hormone receptor expression has been documented in human central nervous system (total brain, spinal cord), anterior pituitary, adrenal, cultured placenta decidual cells, and femur, and in rat central nervous system (thalamus, hypothalamus, anterior pituitary), adrenal medulla, testis, and epididymis. An EST has been isolated from a human brain cancer library.