GNGT1 Products

Recombinant Human GNGT1 Prote ...
Recombinant Human GNGT1 Protein
Species: Hu
Applications: PAGE


GNGT1, also known as Guanine nucleotide-binding protein G(T) subunit gamma-T1, is a 74 amino acid that is 8 kDa, composed of 3 units, alpha, beta and gamma; found in the cell membrane; linked to 7-TM receptors; modulates or transduces in various transmembrane signaling systems; and its beta and gamma chains are requisite for the GTPase activity, for substitution of GDP by GTP, and for G protein-effector interaction. Studies on this protein has shown a relationship with fructose-1,6-bisphosphatase deficiency, retinitis pigmentosa, retinitis, and hypoxia. The GNGT1 protein has also shown an interaction with approx. 300 proteins including GNB1, GNB3, IKBKG, GNAS, and PLEKHB1 in several pathways including chemotaxis CXCR4 signaling pathway, translation regulation by Alpha-1 adrenergic receptors, development activation of ERK by Alpha-1 adrenergic receptors, cytoskeleton remodeling Role of PKA in cytoskeleton reorganization, development A1 receptor signaling, GPCR downstream signaling, transmission across chemical synapses, signaling by GPCR, G protein gated potassium channels, and neuronal system pathway.


Entrez Human
Uniprot Human
Product By Gene ID 2792
Alternate Names
  • guanine nucleotide-binding protein G(T) subunit gamma-T1
  • Transducin gamma chain
  • GNG1
  • guanine nucleotide binding protein (G protein), gamma transducing activitypolypeptide 1

Diseases related to GNGT1

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Retinitis Pigmentosa

Pathways for GNGT1

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Chromosome Localization
Cell Migration
Germ Cell Migration

Research Areas for GNGT1

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Signal Transduction

PTMs for GNGT1

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Bioinformatics Tool for GNGT1

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