GLRB Products

Antibodies
GLRB Antibody
GLRB Antibody
NBP2-30683
Species: Hu, Mouse, Rat
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
GLRB Overexpression Lysate (D ...
GLRB Overexpression Lysate (Denatu...
H00002743-T01
Species: Hu
Applications: WB
Proteins
GLRB Recombinant Protein Anti ...
GLRB Recombinant Protein Antigen
NBP2-30683PEP
Species: Hu
Applications: AC
RNAi
GLRB RNAi
GLRB RNAi
H00002743-R01
Species: Hu

Description

GLRB, also known as Glycine receptor subunit beta, has a 497 amino acid long isoform that is 56 kDa and a short 303 amino acid isoform that is 35 kDa, composed of alpha and beta subunits, responsible for mediating the inhibitory effects of glycine functioning as a neurotransmitter-gated ion channel which produces hyperpolarization via increased chloride conductance due to the binding of glycine to the receptor. Current research is being performed on several diseases and disorders including hyperekplexia, stiff-person syndrome, neurological disorder, autosomal recessive, startle disease, idiopathic generalized epilepsy, spasticity, pharyngitis, neuronitis, and lung cancer. This protein has also been shown to have interactions with GPHN and PFN1 in pathways such as neurophysiological process PGE2-induced pain processing, ligand-gated ion channel transport, transmembrane transport of small molecules, ion channel transport, and neuroactive ligand-receptor interaction.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 2743
Alternate Names
  • beta subunit
  • Glycine receptor 58 kDa subunit
  • glycine receptor, beta

PTMs for GLRB

Learn more about PTMs related to GLRB.

Hydroxylation
Methylation

Bioinformatics Tool for GLRB

Discover related pathways, diseases and genes to GLRB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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