Species: Hu, Mu, Rt, Bv
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Species: Hu
Applications: Binding Activity
Description
Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membraneassociated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-alpha, DAP-1-beta, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP1, through the guanylate kinase domain. SAPAP1 is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. N-terminal splice variants of SAPAP1 are expressed as 95 and 130 kDa proteins. SAPAP1 is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.
Bioinformatics
| Entrez |
Mouse
Rat
Rat
Human
|
| Uniprot |
Human
Human
Human
Rat
Mouse
|
| Product By Gene ID |
9229 |
| Alternate Names |
- DAP1
- DAP-1-ALPHA
- DAP-1DAP-1-BETA
- discs, large (Drosophila) homolog-associated protein 1
- disks large-associated protein 1
- GKAPMGC88156
- hGKAP
- PSD-95/SAP90 binding protein 1
- PSD-95/SAP90-binding protein 1
- SAP90/PSD-95-associated protein 1
- SAPAP1Guanylate kinase-associated protein
|
PTMs for GKAP/DLGAP1
Learn more about PTMs related to GKAP/DLGAP1.
Phosphorylation
Bioinformatics Tool for GKAP/DLGAP1
Discover related pathways, diseases and genes to GKAP/DLGAP1. Need help? Read the
Bioinformatics Tool Guide for instructions on using this tool.
