Geminin Products

Antibodies
Geminin Antibody (1A8)
Geminin Antibody (1A8)
H00051053-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Geminin Antibody
Geminin Antibody
NBP2-16639
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
Geminin Antibody
Geminin Antibody
NB100-40826
Species: Hu
Applications: ICC/IF, IHC, IHC-P, IP, WB (-)
Host: Rabbit Polyclonal
Lysates
Geminin Overexpression Lysate ...
Geminin Overexpression Lysate (Nat...
NBL1-11143
Applications: WB
Proteins
Geminin Recombinant Protein A ...
Geminin Recombinant Protein Antigen
NBP2-56766PEP
Species: Hu
Applications: AC
Geminin Recombinant Protein A ...
Geminin Recombinant Protein Antigen
NBP2-14058PEP
Species: Hu
Applications: AC
Recombinant Human Geminin Pro ...
Recombinant Human Geminin Protein
NBC1-18423
Species: Hu
Applications: PAGE
RNAi
Geminin RNAi
Geminin RNAi
H00051053-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Geminin is a multifunctional nuclear protein invloved in embyro development/differentiation, cell cycle regulation and DNA replciation. Originally defined as an inhibitor of DNA replication and substrate of the anaphase promoting complex, Geminin has also been shown to expand the neural plate in the developing embryos.

Geminin prevents DNA replication by blocking the MCM complex incorporation into prereplication complex (pre-RC). It is absent during the G1 phase and accumulates during the S, G2, and M phases of mitosis. Geminin is then degraded during the metaphase-anaphase trasitio,n allowing replication to occur during subsequent cycles.

Geminin antibodies are useful tools for a variety of research including developmental embryology, stem cell differentiation, neuroscience, and DNA replication studies.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 51053
Alternate Names
  • geminin
  • RP3-369A17.3
  • Gem
  • geminin, DNA replication inhibitor

Bioinformatics Tool for Geminin

Discover related pathways, diseases and genes to Geminin. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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