Gelsolin/GSN Products

Antibodies
Gelsolin/GSN Antibody
Gelsolin/GSN Antibody
Species: Hu, Mu, Rt, Bv, Sh
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Gelsolin/GSN Antibody (893205 ...
Gelsolin/GSN Antibody (893205) [Un...
MAB8170
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC
Host: Mouse Monoclonal
Gelsolin/GSN Antibody (GS-2C4 ...
Gelsolin/GSN Antibody (GS-2C4)
NB110-10067
Species: Hu, Po, Bv, Rb, Rt(-)
Applications: WB, ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, MiAr
Host: Mouse Monoclonal
Antibody Pairs
Gelsolin/GSN Antibody Pair
Gelsolin/GSN Antibody Pair
H00002934-AP21
Species: Hu
Applications: S-ELISA
Gelsolin/GSN Antibody Pair
Gelsolin/GSN Antibody Pair
H00002934-PW2
Species: Hu
Applications: WB, IP
Gelsolin/GSN Antibody Pair
Gelsolin/GSN Antibody Pair
H00002934-PW1
Species: Hu
Applications: WB, IP
Lysates
Gelsolin/GSN Overexpression L ...
Gelsolin/GSN Overexpression Lysate...
H00002934-T01
Species: Hu
Applications: WB
Gelsolin/GSN Overexpression L ...
Gelsolin/GSN Overexpression Lysate...
NBP2-11156
Applications: WB
Proteins
Recombinant Human Gelsolin/GS ...
Recombinant Human Gelsolin/GSN Pro...
H00002934-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human Gelsolin/GS ...
Recombinant Human Gelsolin/GSN Pro...
H00002934-Q01
Species: Hu
Applications: WB, ELISA, PA
Gelsolin/GSN Recombinant Prot ...
Gelsolin/GSN Recombinant Protein A...
NBP2-55565PEP
Species: Hu
Applications: AC
RNAi
Gelsolin/GSN RNAi
Gelsolin/GSN RNAi
H00002934-R02
Species: Hu
Applications: RNAi, RNAi SP
Gelsolin/GSN RNAi
Gelsolin/GSN RNAi
H00002934-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Gelsolin is a calcium regulated actin binding protein. Gelsolin is a regulator of actin filament assembly and disassembly and consists of six homologous subdomains (S1-S6). When C-terminal tail (S6) is bound to calcium ion, it straightens and exposes actin binding sites located on S2s helices, leading to Gelsolin actin-serving activity (1). Gelsolin is inhibited by phosphatidylinositol (4,5)-bisphosphate (PIP2), where PIP2 will bind to S1, S2, and S3 sites. Gelsolin is involved in podosome formation and has been linked to inhibition of apoptosis by preventing release of cytochrome C (2).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 2934
Alternate Names
  • Brevin
  • AGEL
  • brevin
  • ADF
  • Actin-depolymerizing factor
  • DKFZp313L0718
  • gelsolin (amyloidosis, Finnish type)
  • gelsolin

Research Areas for Gelsolin/GSN

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cytoskeleton Markers
Tumor Suppressors

PTMs for Gelsolin/GSN

Learn more about PTMs related to Gelsolin/GSN.

Phosphorylation
Cleavage

Bioinformatics Tool for Gelsolin/GSN

Discover related pathways, diseases and genes to Gelsolin/GSN. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.