GDF-9 Products

Antibodies
GDF-9 Antibody [Unconjugated] ...
GDF-9 Antibody [Unconjugated]
AF739
Species: Mu, Ha
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
GDF-9 Antibody (917319) [Unco ...
GDF-9 Antibody (917319) [Unconjuga...
MAB8266
Species: Hu
Applications: Flow, CyTOF-ready, ICC
Host: Mouse Monoclonal
GDF-9 Antibody - Propeptide
GDF-9 Antibody - Propeptide
AF3536
Species: Mu
Applications: WB
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
Lysates
GDF-9 Overexpression Lysate ( ...
GDF-9 Overexpression Lysate (Denat...
H00002661-T01
Species: Hu
Applications: WB
GDF-9 Overexpression Lysate ( ...
GDF-9 Overexpression Lysate (Native)
NBP2-10477
Applications: WB
Proteins
GDF-9 Recombinant Protein Ant ...
GDF-9 Recombinant Protein Antigen
NBP2-49589PEP
Species: Hu
Applications: AC
Recombinant Human GDF-9 Prote ...
Recombinant Human GDF-9 Protein
NBP1-99374
Species: Hu

Description

GDF9, also known as Growth/differentiation factor 9, is a 454 amino acid that is 51 kDa, is a multifunctional protein required for ovarian folliculogenesis; directly affects oocyte growth and function; stimulates granulosa cell proliferation; promotes primordial follicle development and cell transition from G0/G1 to S; regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells; increases the expression of inhibin B and suppresses FST and FSTL3 production in granulosa-lutein cells. Disease research is currently being studied with relation to GDF9 and polycystic ovary syndrome, premature ovarian failure, blepharophimosis, galactosemia, infertility, gonadal dysgenesis, twinning, prostate cancer, Huntington's disease, endometriosis, prostatitis, breast cancer, and hepatitis B. Interactions with GDF9 protein have been shown to involve SMN1, SMN2, APLP1, GADD45G, TK1, PRKRA and around 50 other interacting proteins in nuclear receptor activation by vitamin-A, paxillin interactions, telomerase components in cell signaling, mitochondrial apoptosis, molecular mechanisms of cancer, antioxidant action of vitamin-C, eIF2 pathway, intracellular calcium signaling, JNK pathway, apoptotic pathways in synovial fibroblasts plus 44 more other pathways.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 2661
Alternate Names
  • growth/differentiation factor 9
  • GDF-9
  • growth differentiation factor 9

Research Areas for GDF-9

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research

Bioinformatics Tool for GDF-9

Discover related pathways, diseases and genes to GDF-9. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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