GATM Products

Description

This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.

Bioinformatics

Entrez	2628 Human
Uniprot	NP_001473.1 Human
Product By Gene ID	2628
Alternate Names	AGATtransamidinase AT EC 2.1.4 EC 2.1.4.1 glycine amidinotransferase (L-arginine:glycine amidinotransferase) glycine amidinotransferase, mitochondrial L-arginine:glycine amidinotransferase Transamidinase

Research Areas for GATM

Find related products by research area and learn more about each of the different research areas below.

Amino Acids, Drugs and other small molecules
Cancer
Signal Transduction