WB, IHC, ChIP, ICC/IFHost:
Species: Hu, Mk
Applications: WB, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
Applications: WB, ELISA, PA, PAGE, AP
Applications: RNAi, RNAi SP
The Gata6 gene is a transcriptional activator that is crucial to modulating terminal differentiation and/or proliferation by regulating SEMA3C and PLXNA2. The Gata6 gene is most prominent during vertebrate development in early and later embryogenesis. Two isoforms exist: isoform 1 is 595 amino acids long at 60 kDa and isoform 2 exists at 449 amino acids in length and 45 kDA. The Gata6 gene focuses on endo- and mesodermally derived cells, thus participating significantly in gut, lung, and heart development and mutations of the Gata6 gene are linked to multiple congenital defects. The Gata6 gene has also been associated with polycystic ovary syndrome, hernias, teratoma, pulmonary fibrosis, germ cell tumor, gastric cancer, Crohn's disease, colorectal cancer, colon cancer, and carcinoma. It is known to interact with KLF13, MED1, HHEX, KLF2, and SP1 as it functions in pathways such as lymphocyte signaling, heart development, hemostasis, and thrombin signaling.
|Product By Gene ID
- transcription factor GATA-6
- GATA-binding factor 6
- GATA-binding protein 6
- GATA binding protein 6
Bioinformatics Tool for GATA-6
Discover related pathways, diseases and genes to GATA-6. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.