GATA-1 Products

Antibodies
GATA-1 Antibody
GATA-1 Antibody
NBP1-84792
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
GATA-1 Antibody (4F5)
GATA-1 Antibody (4F5)
NBP1-47492
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Mouse Monoclonal
GATA-1 Antibody
GATA-1 Antibody
NB100-81935
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
GATA-1 Antibody Pair
GATA-1 Antibody Pair
H00002623-PW1
Species: Hu
Applications: WB, IP
Lysates
GATA-1 Overexpression Lysate ...
GATA-1 Overexpression Lysate (Native)
NBP2-04216
Applications: WB
GATA-1 Overexpression Lysate ...
GATA-1 Overexpression Lysate (Dena...
H00002623-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human GATA-1 Prot ...
Recombinant Human GATA-1 Protein
H00002623-P02
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human GATA-1 Prot ...
Recombinant Human GATA-1 Protein
H00002623-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human GATA-1 Prot ...
Recombinant Human GATA-1 Protein
H00002623-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
GATA-1 RNAi
GATA-1 RNAi
H00002623-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

GATA1 (Globin transcription factor 1) is a Cys2/Cys2 zinc finger DNA binding protein that is expressed primarily in erythroid, megakaryocytic, mast cells and eosinophilic cells. It belongs to the GATA family of transcription factors. GATA1 is a transcriptional activator which probably serves as a general switch factor for erythroid development. It binds to DNA sites with the consensus sequence [AT]GATA[AG] within regulatory regions of globin genes and of other genes expressed in erythroid cells. The protein also plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia. Acquired somatic mutations in GATA1 occur in virtually all children with Down's Syndrome, congenital transient myeloproliferative syndrome (TMD) and acute megakaryocytic leukemia.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2623
Alternate Names
  • NF-E1 DNA-binding protein
  • Eryf1
  • GATA-binding factor 1
  • transcription factor GATA1
  • GF-1
  • GF1globin transcription factor 1
  • NFE1erythroid transcription factor 1
  • GATA-1erythroid transcription factor
  • ERYF1GATA-binding protein 1 (globin transcription factor 1)
  • XLTT
  • GATA binding protein 1 (globin transcription factor 1)

Research Areas for GATA-1

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Stem Cell Markers

Bioinformatics Tool for GATA-1

Discover related pathways, diseases and genes to GATA-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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