GABA-B R2 Products

Antibodies
GABA-B R2 Antibody [Unconjuga ...
GABA-B R2 Antibody [Unconjugated] ...
AF1188
Species: Rt
Applications: WB, IHC
Host: Goat Polyclonal
GABA-B R2 [p Ser892] Antibody ...
GABA-B R2 [p Ser892] Antibody [Unc...
PPS073
Species: Hu, Mu, Rt, Xp
Applications: WB, IF
Host: Rabbit Polyclonal
Lysates
GABA-B R2 Overexpression Lysa ...
GABA-B R2 Overexpression Lysate (N...
NBL1-10910
Species: Hu
Applications: WB
Proteins
Recombinant Human GABA-B R2 P ...
Recombinant Human GABA-B R2 Protein
H00009568-P01
Species: Hu
Applications: WB, ELISA, PA
GABA-B R2 Recombinant Protein ...
GABA-B R2 Recombinant Protein Antigen
NBP2-49520PEP
Species: Hu
Applications: AC
GABA-B R2 Recombinant Protein ...
GABA-B R2 Recombinant Protein Antigen
NBP2-48516PEP
Species: Hu
Applications: AC
RNAi
GABA-B R2 RNAi
GABA-B R2 RNAi
H00009568-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled receptors that mediate slow synaptic inhibition in the central nervous system. Moss and colleagues (Couve, et al., 2002) recently demonstrated that the functional coupling of GABAB R1/GABAB R2 receptors to inwardly rectifying K+ channels rapidly desensitizes. This effect is alleviated after direct phosphorylation of a single serine residue (Ser892) in the cytoplasmic tail of GABAB R2 by cyclic AMP (cAMP)-dependent protein kinase (PKA). In addition to it postsynaptic effects GABAB receptors localized to the presynaptic region have been reported to restrict the availability of synaptic vesicles for release (Sakaba and Neher, 2003).

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Rat
Product By Gene ID 9568
Alternate Names
  • Gb2
  • GABA-BR2
  • gb2
  • GABA-B-R2
  • gamma-aminobutyric acid type B receptor subunit 2
  • G protein-coupled receptor 51
  • GPR51GABA-B receptor, R2 subunit
  • HG20HRIHFB2099
  • GPRC3BFLJ36928
  • GABABR2GABA-B receptor 2
  • G-protein coupled receptor 51
  • gamma-aminobutyric acid (GABA) B receptor, 2

Research Areas for GABA-B R2

Find related products by research area and learn more about each of the different research areas below.

GPCR
Neuronal Cell Markers
Neuroscience
Neurotransmission
Phospho-Specific

PTMs for GABA-B R2

Learn more about PTMs related to GABA-B R2.

Phosphorylation
Glycosylation

Bioinformatics Tool for GABA-B R2

Discover related pathways, diseases and genes to GABA-B R2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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