FosB/G0S3 Products

Antibodies
FosB/G0S3 Antibody
FosB/G0S3 Antibody
AF2214
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
FosB/G0S3 Antibody (269928)
FosB/G0S3 Antibody (269928)
MAB2214
Species: Hu, Mu
Applications: WB
Host: Mouse Monoclonal
Antibody Pairs
FosB/G0S3 Antibody Pair
FosB/G0S3 Antibody Pair
H00002354-PW1
Species: Hu
Applications: WB, IP
Lysates
FosB/G0S3 Overexpression Lysa ...
FosB/G0S3 Overexpression Lysate (D...
H00002354-T01
Species: Hu
Applications: WB
FosB/G0S3 Overexpression Lysa ...
FosB/G0S3 Overexpression Lysate (N...
NBL1-10795
Applications: WB
Proteins
FosB/G0S3 Partial Recombinant ...
FosB/G0S3 Partial Recombinant Protein
H00002354-Q01
Species: Hu
Applications: WB, ELISA, PA
FosB/G0S3 Recombinant Protein ...
FosB/G0S3 Recombinant Protein
H00002354-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
FosB/G0S3 RNAi
FosB/G0S3 RNAi
H00002354-R01
Species: Hu

Description

Fos and Jun dimerize to form Activator Protein-1 (AP-1), a transcriptional factor that binds to the 12-O-tetradecanoylphorbol 13-acetate (TPA) response element (TRE) of several cellular and viral genes including human collagenase, metallothionein IIa, stromelysin, interleukin 2, SV40 and polyoma. Fos and Jun contain the 'leucine-zipper' motif that allows for dimerization and an adjacent basic domain required for biological activity. The functionally active form of Fos is in a heterodimer with a member of the Jun family. While Jun family members can form functional homodimers, studies indicate that Fos family members do not self-associate and therefore do not bind DNA on their own. The various dimers differ in their ability to transactivate AP-1 dependent genes.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 2354
Alternate Names
  • GOSB
  • protein fosB
  • GOS3
  • oncogene FOS-B
  • DKFZp686C0818
  • activator protein 1
  • AP-1
  • G0S3G0/G1 switch regulatory protein 3
  • MGC42291
  • FBJ murine osteosarcoma viral oncogene homolog B

Research Areas for FosB/G0S3

Find related products by research area and learn more about each of the different research areas below.

Cancer
Tumor Suppressors

Bioinformatics Tool for FosB/G0S3

Discover related pathways, diseases and genes to FosB/G0S3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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