Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu, RM
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
Species: Hu
Applications: IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase andis subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidationcapacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the enzyme, FMO1 found in fetal liver, FMO2found in adult liver, and FMO3 are encoded by genes clustered in the 1q23-q25 region. Flavin-containing monooxygenasesare NADPH-dependent flavoenzymes that catalyzes the oxidation of soft nucleophilic heteroatom centers in drugs,pesticides, and xenobiotics. (provided by RefSeq)
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
2326 |
| Alternate Names |
- dimethylaniline monooxygenase [N-oxide-forming] 1
- Dimethylaniline oxidase 1
- EC 1.14.13.8
- Fetal hepatic flavin-containing monooxygenase 1
- flavin containing monooxygenase 1
- Flavin-containing monooxygenase 1 (fetal liver)
- FMO 1
|
