FLNC Products

Antibodies
FLNC Antibody
FLNC Antibody
NBP1-89300
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
FLNC Partial Recombinant Prot ...
FLNC Partial Recombinant Protein
H00002318-Q01
Species: Hu
Applications: WB, ELISA, PA
FLNC Recombinant Protein Anti ...
FLNC Recombinant Protein Antigen
NBP1-89300PEP
Species: Hu
Applications: AC
RNAi
FLNC RNAi
FLNC RNAi
H00002318-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The FLNC gene encodes a filamin-c protein (muscle specific) that in isoform 1 is 2,725 amino acids long, 291 kDA and in isoform 2 is 2,692 amino acids long at 287 kDA. The protein is thought to be critical in large actin-cross-linking protein, especially in reorganizing the actin cytoskeleton after reacting to signaling events. FLNC is essential for normal myogenesis and for regulating the structural integrity of muscle fibers. FLNC is active in the SMAD signaling network, ILK signaling, cytoskeletal signaling, MAPK signaling pathway, focal adhesion, and cell to cell communication. Defects in this gene cause myopathy myofibrillar type 5 as well as myopathy distal type 4. FLNC has also been linked to cystic fibrosis, gastric cancer, muscular dystrophy, bronchiectasis, paget's disease of the bone, myofribrillar myopathy, xanthomatosis, asthma, aspergillosis, and limb-girdle muscular dystrophy.

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 2318
Alternate Names
  • Gamma-filamin
  • ABP280A
  • Filamin-2
  • filamin C, gamma (actin binding protein 280)
  • FLNc
  • ABPA
  • ABP-L
  • ABP-280-like protein
  • filamin-C
  • FLN-C
  • filamin-2
  • Actin-binding-like protein
  • filamin 2
  • ABP-280
  • FLN2actin binding protein 280
  • ABPLABP-L, gamma filamin
  • FLJ10186
  • filamin C, gamma

PTMs for FLNC

Learn more about PTMs related to FLNC.

Methylation
Demethylation
Cleavage

Bioinformatics Tool for FLNC

Discover related pathways, diseases and genes to FLNC. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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