FBXW5 Products

Antibodies
FBXW5 Antibody
FBXW5 Antibody
NBP1-91892
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
FBXW5 Antibody
FBXW5 Antibody
NBP2-16455
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
FBXW5 Antibody
FBXW5 Antibody
H00054461-B01P
Species: Hu
Applications: WB, ELISA
Host: Mouse Polyclonal
Lysates
FBXW5 Overexpression Lysate ( ...
FBXW5 Overexpression Lysate (Denat...
H00054461-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human FBXW5 Prote ...
Recombinant Human FBXW5 Protein
H00054461-Q01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human FBXW5 Prote ...
Recombinant Human FBXW5 Protein
H00054461-P01
Species: Hu
Applications: WB, ELISA, PA
FBXW5 Recombinant Protein Ant ...
FBXW5 Recombinant Protein Antigen
NBP1-91892PEP
Species: Hu
Applications: AC

Description

The FBXW5 gene encodes a F-box/WD repeat-containing protein 5 that exists in two isoforms. Isoform 1 is 556 amino acids long, at nearly 64 kDA while isoform 2 is 377 amino acids long at 42 kDA. This protein encoded by this gene functions in substrate recognition of SCF as well as DCX E3 ubiquitin-protein ligase complexes. It may also work as a negative regulator of MAP3K7/TAK1 signaling in the interleukin-1B signaling pathway. FBXW5 participates in protein chaperonin-mediated protein folding and metabolism as well as the association of TriC/CCT with target proteins during biosynthesis. It is known to interact with genes CUL1, MDFI, SKP1, KRTAP4-12, and UBE2R2. FBXW5 is associated with tuberous sclerosis as well as hepatitis b.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 54461
Alternate Names
  • DKFZP434B205
  • FBW5
  • F-box and WD-40 domain-containing protein 5
  • WD repeat-containing F-box protein FBW5
  • F-box and WD-40 domain protein 5
  • F-box/WD repeat-containing protein 5
  • MGC20962
  • RP11-229P13.10
  • Fbw5
  • DKFZp434B205
  • F-box and WD repeat domain containing 5

Diseases related to FBXW5

Discover more about diseases related to FBXW5.

Cell Transformation, Neoplastic
Neoplasms

Pathways for FBXW5

View related products by pathway and learn more about each of the pathways below.

Cell Cycle
Mitosis
Centrosome Duplication
Localization

PTMs for FBXW5

Learn more about PTMs related to FBXW5.

Phosphorylation
Sumoylation
Ubiquitination

Bioinformatics Tool for FBXW5

Discover related pathways, diseases and genes to FBXW5. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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