FATP2/SLC27A2 Products

Description

SLC27A2 is encoded by this gene is an isozyme of long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme activates long-chain, branched-chain and very-long-chain fatty acids containing 22 or more carbons to their CoA derivatives. It is expressed primarily in liver and kidney, and is present in both endoplasmic reticulum and peroxisomes but not in mitochondria. Its decreased peroxisomal enzyme activity is in part responsible for the biochemical pathology in X-linked adrenoleukodystrophy. [provided by RefSeq]

Bioinformatics

Entrez	11001 Human
Uniprot	AAH57770.1 Human NP_003636 Human
Product By Gene ID	11001
Alternate Names	ACSVL1FATP-2 EC 6.2.1 EC 6.2.1.- EC 6.2.1.3 EC 6.2.1.7 FACVL1very long-chain fatty-acid-coenzyme A ligase 1 FATP2THCA-CoA ligase Fatty acid transport protein 2 Fatty-acid-coenzyme A ligase, very long-chain 1 hFACVL1 HsT17226 Long-chain-fatty-acid--CoA ligase solute carrier family 27 (fatty acid transporter), member 2 Solute carrier family 27 member 2 very-long-chain acyl-CoA synthetase VLACSVery long-chain-fatty-acid-CoA ligase VLCSvery long-chain acyl-CoA synthetase