Factor VIII Products

Antibodies
Antibody Pairs
Factor VIII Antibody Pair
Factor VIII Antibody Pair
H00002157-PW1
Species: Hu
Applications: WB, IP
Lysates
Factor VIII Overexpression Ly ...
Factor VIII Overexpression Lysate ...
H00002157-T01
Species: Hu
Applications: WB
Factor VIII Overexpression Ly ...
Factor VIII Overexpression Lysate ...
NBL1-10413
Applications: WB
Proteins
Factor VIII Partial Recombina ...
Factor VIII Partial Recombinant Pr...
H00002157-Q01
Species: Hu
Applications: WB, ELISA, PA
Factor VIII Recombinant Prote ...
Factor VIII Recombinant Protein
H00002157-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Factor VIII RNAi
Factor VIII RNAi
H00002157-R01
Species: Hu
Factor VIII RNAi
Factor VIII RNAi
H00002157-R02
Species: Hu

Description

Von Willebrand Factor (VWF) was previously known as Factor VIII related antigen. VWF is synthesized exclusively by endothelial cells and megakaryocytes, and stored in the intracellular granules or constitutively secreted into plasma. This glycoprotein functions as both an antihemophilic factor carrier and a platelet vessel wall mediator in the blood coagulation system. Important in the maintenance of homeostasis, it participates in platelet vessel wall interactions by forming a noncovalent complex with coagulation factor VIII at the site of vascular injury. The Von Willebrand factor has functional binding domains to platelet glycoprotein Ib, glycoprotein IIb/IIIa, collagen and heparin. Mutations in this gene or deficiencies in this protein result in Von Willebrand's disease. VWD is characterized by frequent bleeding (gingival, minor skin quantitative lacerations, menorrhagia, etc.).

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 2157
Alternate Names
  • Procoagulant component
  • Antihemophilic factor
  • factor VIII F8B
  • FVIII
  • coagulation factor VIIIc
  • DXS1253E
  • F8Ccoagulation factor VIII
  • HEMAF8B
  • AHF
  • coagulation factor VIII, procoagulant component

Bioinformatics Tool for Factor VIII

Discover related pathways, diseases and genes to Factor VIII. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Factor VIII Blog Posts

Check out the latest blog posts on Factor VIII.
Factor VIII - a key factor in the clotting process
Hemostasis, or blood clotting, follows tissue injury and involves the deployment of essential plasma procoagulants (such as prothrombin, and Factors X, IX, V, and VIII) that trigger the blood coagulation cascade. This cascade leads to the formation...    Read more.
Read more Factor VIII related blogs.