Factor V Products

Antibodies
Factor V Antibody
Factor V Antibody
NBP1-88114
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
Factor V Antibody Pair [HRP]
Factor V Antibody Pair [HRP]
NBP2-42116
Species: Hu
Applications: S-ELISA
Host: Polyclonal
Proteins
Factor V Partial Recombinant ...
Factor V Partial Recombinant Protein
H00002153-Q01
Species: Hu
Applications: WB, ELISA, PA
Factor V Recombinant Protein ...
Factor V Recombinant Protein Antigen
NBP1-88114PEP
Species: Hu
Applications: AC
Factor V Native Protein
Factor V Native Protein
NBP2-12562
Species: Hu
RNAi
Factor V RNAi
Factor V RNAi
H00002153-R01
Species: Hu

Description

The F5 gene encodes a 2,224 amino acid long, 251 kDA coagulation factor V protein that is critical in the regulation of homeostasis. Additionally, F5 functions as a cofactor for the prothrombinase activity of factor Xa which results in the initiation of prothrombin to thrombin. F5 participates in blood coagulation signaling pathways, the blood clotting cascade, platelet degranulation as well as activation, signaling, and aggregation, and in responses to elevated platelet cytosolic Ca2+. It interacts with genes PROC, PROS1, F2, MMRN1, and CALR. Defects in F5 cause factor 5 deficiency (owren parahemophilia), thrombophilia due to activated protein C resistance, susceptibility to Budd-Chiari syndrome, susceptibility to ischemic strokes, and susceptibility to pregnancy loss, recurrent, type 1. F5 is also linked to deep vein thrombosis, antithrombin III deficiency, retinal vein occlusion, legg-calve-perthes disease, liver disease, hypertension, pulmonary embolism, lupus, and patent foramen ovale.

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 2153
Alternate Names
  • factor V Leiden
  • FVL
  • coagulation factor V jinjiang A2 domain
  • Proaccelerin, labile factor
  • coagulation factor V
  • Activated protein C cofactor
  • PCCF
  • coagulation factor V (proaccelerin, labile factor)

PTMs for Factor V

Learn more about PTMs related to Factor V.

Phosphorylation
Cleavage
Methylation
Oxidation
Reduction
Glycosylation
Carboxylation
Biotinylation

Bioinformatics Tool for Factor V

Discover related pathways, diseases and genes to Factor V. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related Factor V Blog Posts

Check out the latest blog posts on Factor V.
Factor VIII - a key factor in the clotting process
Hemostasis, or blood clotting, follows tissue injury and involves the deployment of essential plasma procoagulants (such as prothrombin, and Factors X, IX, V, and VIII) that trigger the blood coagulation cascade. This cascade leads to the formation...    Read more.
Read more Factor V related blogs.