ERp72 Products

Antibodies
ERp72 Antibody (2B9)
ERp72 Antibody (2B9)
Species: Hu, Rt, Ca, Pm
Applications: WB, IHC, IHC-P
Host: Mouse Monoclonal
ERp72 Antibody
ERp72 Antibody
NBP2-16371
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
ERp72 Antibody
ERp72 Antibody
NBP1-84794
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ERp72 Overexpression Lysate ( ...
ERp72 Overexpression Lysate (Denat...
H00009601-T01
Species: Hu
Applications: WB
ERp72 Overexpression Lysate ( ...
ERp72 Overexpression Lysate (Native)
NBL1-14245
Applications: WB
Proteins
ERp72 Recombinant Protein Ant ...
ERp72 Recombinant Protein Antigen
NBP1-84795PEP
Species: Hu
Applications: AC
ERp72 Recombinant Protein Ant ...
ERp72 Recombinant Protein Antigen
NBP1-84794PEP
Species: Hu
Applications: AC
Recombinant Human ERp72 Prote ...
Recombinant Human ERp72 Protein
NBP2-52141
Species: Hu
Applications: PAGE
RNAi
ERp72 RNAi
ERp72 RNAi
H00009601-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

ERp72 is an endoplasmic reticulum luminal protein that is both a stress protein and a member of the protein disulfide isomerase family of proteins. Sequence analysis of ERp72 shows that it shares sequence identity with PDI (protein disulphide isomerase) at three discrete regions, as well as containing the ER retention signal KEEL at its C-terminus. ERp72 is shown to have three copies of sequence believed to be CGHC-containing active sites, which are also found in PDI. These CGHC sites are critical sites that are involved in the protein disulphide isomerization process. These results suggest that ERp72 is a newly described member of the family of CGHC-containing proteins that functions as a molecular chaperone. This antibody was raised by a genetic immunization technique. Genetic immunization can be used to generate antibodies by directly delivering antigen-coding DNA into the animal, rather than injecting a protein or peptide (Tang et al. PubMed: 1545867; Chambers and Johnston PubMed 12910245; Barry and Johnston PubMed: 9234514). The animal's cells produce the protein, which stimulates the animal's immune system to produce antibodies against that particular protein. A vector coding for a partial fusion protein was used for genetic immunisation of a mouse and the resulting serum was tested in Western blot against an E.coli lysate containing that partial fusion protein. Genetic immunization offers enormous advantages over the traditional protein-based immunization method. DNA is faster, cheaper and easier to produce and can be produced by standard techniques readily amenable to automation. Furthermore, the antibodies generated by genetic immunization are usually of superior quality with regard to specificity, affinity and recognizing the native protein.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 9601
Alternate Names
  • ERp72
  • ERp-72
  • ERp70
  • Endoplasmic reticulum resident protein 72
  • protein disulfide-isomerase A4
  • Endoplasmic reticulum resident protein 70
  • intestinal-related)
  • protein disulfide isomerase related protein (calcium-binding protein
  • protein disulfide isomerase-associated 4
  • ERP72EC 5.3.4.1
  • ERP70ER protein 72
  • ER protein 70
  • protein disulfide isomerase family A, member 4

Pathways for ERp72

View related products by pathway and learn more about each of the pathways below.

Transport
Mrna Splicing
Oocyte Development
Translation
Electron Transport

Research Areas for ERp72

Find related products by research area and learn more about each of the different research areas below.

Core ESC-Like Genes
Membrane Trafficking and Chaperones
Stem Cell Markers

PTMs for ERp72

Learn more about PTMs related to ERp72.

Phosphorylation
Cleavage

Bioinformatics Tool for ERp72

Discover related pathways, diseases and genes to ERp72. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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