ERO1LB Products

Antibodies
ERO1LB Antibody
ERO1LB Antibody
NBP1-83961
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
ERO1LB Overexpression Lysate ...
ERO1LB Overexpression Lysate (Native)
NBL1-10336
Applications: WB
Proteins
Recombinant Human ERO1LB Prot ...
Recombinant Human ERO1LB Protein
H00056605-P01
Species: Hu
Applications: WB, ELISA, PA
ERO1LB Recombinant Protein An ...
ERO1LB Recombinant Protein Antigen
NBP1-83961PEP
Species: Hu
Applications: AC

Description

Essential oxidoreductase that oxidizes proteins in the endoplasmic reticulum to produce disulfide bonds. Acts by oxidizing directly P4HB/PDI isomerase through a direct disulfide exchange. Does not act as a direct oxidant of folding substrate, but relies on P4HB/PDI to transfer oxidizing equivalent. Associates with ERP44 but not with GRP54, demonstrating that it does not oxidize all PDI related proteins and can discriminate between PDI and related proteins. Its reoxidation probably involves electron transfer to molecular oxygen via FAD. Acts independently of glutathione. May be responsible for a significant proportion of reactive oxygen species (ROS) in the being a source of oxidative stress. Required for the folding of cell, thereby being a source of oxidative stress

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 56605
Alternate Names
  • EC 1.8.4
  • DKFZp779I0141
  • Oxidoreductin-1-L-beta
  • DKFZp779C1042
  • EC 1.8.4.-
  • ERO1-L(beta)
  • oxidoreductin-1-L-beta
  • ERO1-L-beta
  • ERO1-like protein beta
  • Endoplasmic oxidoreductin-1-like protein B
  • FLJ11003
  • ERO1-like beta (S. cerevisiae)

Pathways for ERO1LB

View related products by pathway and learn more about each of the pathways below.

Protein Folding
Secretion
Glucose Homeostasis
Secretory Pathway
Aging
Localization
Immunoglobulin Secretion

PTMs for ERO1LB

Learn more about PTMs related to ERO1LB.

Oxidation

Bioinformatics Tool for ERO1LB

Discover related pathways, diseases and genes to ERO1LB. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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