EphB3 Products

Description

Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene is a receptor for ephrin-B family members.

Bioinformatics

Entrez	13643 Mouse 2049 Human
Uniprot	NM_004443 Human NP_004434 Human NP_004434.2 Human P54753 Human
Product By Gene ID	2049
Alternate Names	EC 2.7.10 EC 2.7.10.1 EK2 EPH receptor B3 EphB3 EPH-like kinase 2 EPH-like tyrosine kinase-2 ephrin type-B receptor 3 ETK2Hek2 HEK2 hEK2 human embryo kinase 2 TYRO6 Tyro6 Tyrosine-protein kinase TYRO6

Research Areas for EphB3

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Protein Kinase