EphA2 Products

Description

Eph receptor A2 belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands.

Bioinformatics

Entrez	1969 Human 13836 Mouse
Uniprot	NP_004422 Human NP_004422.2 Human P29317 Human AAH37166 Human
Product By Gene ID	1969
Alternate Names	EphA2 EC 2.7.10 ARCC2 Epithelial cell kinase EC 2.7.10.1 soluble EPHA2 variant 1 Tyrosine-protein kinase receptor ECK ECKepithelial cell receptor protein tyrosine kinase ephrin type-A receptor 2 EPH receptor A2

Diseases related to EphA2

Discover more about diseases related to EphA2.

Neoplasms
Malignant Neoplasms
Carcinoma
Neoplasm Metastasis
Tissue Adhesions
Tumor Angiogenesis
Pathologic Neovascularization
Cell Invasion
Malignant Paraganglionic Neoplasm
Mammary Neoplasms
Malignant Neoplasm Of Breast
Cell Transformation, Neoplastic
Melanoma
Tumor Progression
Malignant Neoplasm Of Prostate
Neoplasm Invasiveness
Adenocarcinoma
Malignant Neoplasm Of Ovary
Ovarian Neoplasm

Pathways for EphA2

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Angiogenesis
Cell Migration
Cell Adhesion
Cell Proliferation
Cell Growth
Pathogenesis
Localization
Axon Guidance
Oncogenesis
Gene Silencing
Cell Cycle
Endocytosis
Rna Interference
Cell Motility
Endothelial Cell Migration
Transport
Cell Cycle Arrest
Cell-cell Adhesion
Tube Formation
Translation

Research Areas for EphA2

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Cancer
Protein Kinase

PTMs for EphA2

Learn more about PTMs related to EphA2.

Phosphorylation
Dephosphorylation
Cleavage
Methylation
Glycosylation
Ubiquitination
Carboxylation
Ribosylation

Bioinformatics Tool for EphA2

Discover related pathways, diseases and genes to EphA2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 

Related EphA2 Blog Posts

Check out the latest blog posts on EphA2.

Repurposing FDA-approved drugs to combat the rise of antibiotic resistance By Beth Melson, MSAntibiotic resistance is a global threat to public health. Widespread, inappropriate use of antibiotics, such as to treat viral infections or promote growth in livestock, has led to increased incid...    Read more.

Read more EphA2 related blogs.