EPB41L3 Products

Description

Band 4.1-like protein 3 (EPB41L3) is a critical growth regulator in the pathogenesis of meningiomas. EPB41L3 is highly Expressed in the brain, with lower levels found in the kidneys, intestines, and testis.

EPB41L3 is a member of a family of similar proteins whose expression is frequently lost in a variety of human tumors, including meningiomas, non-small-cell lung cancers, and breast carcinomas. It is also frequently down-regulated in human clinical prostate cancer. Studies have shown that Protein 4.1B normally triggers death in metastatic cells, thereby preventing cancer from spreading. A clinical test for Protein 4.1B activity could be useful in assessing the metastatic potential of prostate cancers. Therefore, EPB41L3 antibodies may be very useful for cancer research.

Bioinformatics

Entrez	116724 Rat 13823 Mouse 23136 Human
Uniprot	AAH06141.1 Human AB023204 (Human) Human NP_036439 Human NP_036439.2 Human Q9Y2J2 Human
Product By Gene ID	23136
Alternate Names	4.1BFLJ37633 DAL1DAL-1, Differentially expressed in adenocarcinoma of the lung protein 1 erythrocyte membrane protein band 4.1-like 3 KIAA0987band 4.1-like protein 3

Research Areas for EPB41L3

Find related products by research area and learn more about each of the different research areas below.

Cancer
Cytoskeleton Markers
Signal Transduction
Tumor Suppressors