ENC1 Products

Antibodies
ENC1 Antibody
ENC1 Antibody
NBP1-77146
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Chicken Polyclonal
ENC1 Antibody (3B1)
ENC1 Antibody (3B1)
H00008507-M02
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
ENC1 Antibody (3C10)
ENC1 Antibody (3C10)
H00008507-M03
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
ENC1 Overexpression Lysate (N ...
ENC1 Overexpression Lysate (Native)
NBL1-10263
Applications: WB
Proteins
ENC1 Partial Recombinant Prot ...
ENC1 Partial Recombinant Protein
H00008507-Q01
Species: Hu
Applications: WB, ELISA, PA
ENC1 Recombinant Protein
ENC1 Recombinant Protein
H00008507-P01
Species: Hu
Applications: WB, ELISA, PA
ENC1 Peptide
ENC1 Peptide
NBP1-77146PEP
Species: Hu
Applications: AC
RNAi
ENC1 RNAi
ENC1 RNAi
H00008507-R01
Species: Hu

Description

DNA damage and/or hyperproliferative signals activate wildtype p53 tumor suppressor protein (TP53; MIM 191170), inducing cell cycle arrest or apoptosis. Mutations that inactivate p53 occur in 50% of all tumors. Polyak et al. (1997) [PubMed 9305847] used serial analysis of gene expression (SAGE) to evaluate cellular mRNA levels in a colorectal cancer cell line transfected with p53. Of 7,202 transcripts identified, only 14 were expressed at levels more than 10-fold higher in p53-expressing cells than in control cells. Polyak et al. (1997) [PubMed 9305847] termed these genes 'p53-induced genes,' or PIGs, several of which were predicted to encode redox-controlling proteins. They noted that reactive oxygen species (ROS) are potent inducers of apoptosis. Flow cytometric analysis showed that p53 expression induces ROS production, which increases as apoptosis progresses under some conditions. The authors stated that the PIG10 gene, also called ENC1, encodes an actin-binding protein.[supplied by OMIM]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 8507
Alternate Names
  • tumor protein p53 inducible protein 10
  • CCL28
  • ENC-1BTB domain-like (brain)
  • PIG10KLHL35
  • FLJ39259
  • ectodermal-neural cortex 1 (with BTB-like domain)

Research Areas for ENC1

Find related products by research area and learn more about each of the different research areas below.

Neuroscience

PTMs for ENC1

Learn more about PTMs related to ENC1.

Cleavage
Methylation
Ubiquitination

Bioinformatics Tool for ENC1

Discover related pathways, diseases and genes to ENC1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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