EMAP-II/AIMP1 Products

Antibodies
EMAP-II/AIMP1 Antibody (95951 ...
EMAP-II/AIMP1 Antibody (959516) [U...
MAB1910
Species: Hu, Mu, Rt
Applications: WB, IHC, ICC
Host: Mouse Monoclonal
EMAP-II/AIMP1 Antibody
EMAP-II/AIMP1 Antibody
NBP2-27206
Species: Hu, Mu, Rt, Po, Bv, Ca, ChHa, Eq, Fe, GP, Op, Other, Pm
Applications: WB, IHC-P
Host: Rabbit Polyclonal
EMAP-II/AIMP1 Antibody
EMAP-II/AIMP1 Antibody
NBP2-27080
Species: Hu, Mu, Rt, Po, Bv, ChHa, Eq, GP, Other, Pm
Applications: WB, Simple Western
Host: Rabbit Polyclonal
Proteins
EMAP-II/AIMP1 Recombinant Pro ...
EMAP-II/AIMP1 Recombinant Protein ...
NBP1-84851PEP
Species: Hu
Applications: AC
EMAP-II/AIMP1 Recombinant Pro ...
EMAP-II/AIMP1 Recombinant Protein
P3601
Species: Hu
Applications: Func, PAGE
EMAP-II/AIMP1 Recombinant Pro ...
EMAP-II/AIMP1 Recombinant Protein
NBP1-99382
Species: Hu
RNAi
EMAP-II/AIMP1 RNAi
EMAP-II/AIMP1 RNAi
H00009255-R01
Species: Hu

Description

EMAP II (Endothelial-Monocyte-Activating Polypeptide II) is a proinflammatory cytokine and chemoattractant of macrophages and polymorphonuclear lymphocytes. EMAP II is synthesized as a 34 kDa precursor molecule which is cleaved to a biologically active 22 kDa mature polypeptide. This active protein is known to induce the procoagulant protein tissue factor on the surface of endothelial cells and modulate other properties of endothelial cells and monocytes in vitro, including the stimulation of TNF-alpha and myeloperoxidase. EMAP II activates neutrophils in vivo and induces an inflammatory reaction and tumor regression. EMAP II induces apoptosis in proliferating endothelial cells and inhibits neovascularization. This anti-angiogenic property is of interest to tumor biology. EMAP II is also a negative modulator of lung vascular growth.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 9255
Alternate Names
  • multisynthetase complex auxiliary component p43
  • Multisynthase complex auxiliary component p43
  • endothelial-monocyte activating polypeptide II
  • EMAPIImember 1 (endothelialmonocyte-activating)
  • EMAP-2
  • aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

Research Areas for EMAP-II/AIMP1

Find related products by research area and learn more about each of the different research areas below.

Biologically Active Proteins
Cytokine Research

PTMs for EMAP-II/AIMP1

Learn more about PTMs related to EMAP-II/AIMP1.

Phosphorylation
Cleavage
Ubiquitination

Bioinformatics Tool for EMAP-II/AIMP1

Discover related pathways, diseases and genes to EMAP-II/AIMP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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